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新型冠状病毒肺炎患者的自发性纵隔气肿和皮下气肿

Spontaneous pneumomediastinum and subcutaneous emphysema in patients with COVID-19.

作者信息

Wadhawa Reema, Thakkar Avani, Chhanwal Heena Sunil, Bhalotra Anju, Rana Yashpal, Wadhawa Vivek

机构信息

Department of Anesthesia, GCS Medical College, Hospital and Research Centre, Ahmedabad, Gujarat, India.

Department of Anesthesia, Maulana Azad Medical College, Asarwa, Ahmedabad, Gujarat, India.

出版信息

Saudi J Anaesth. 2021 Apr-Jun;15(2):93-96. doi: 10.4103/sja.sja_939_20. Epub 2021 Apr 1.

DOI:10.4103/sja.sja_939_20
PMID:34188623
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8191243/
Abstract

BACKGROUND

Coronavirus disease 2019 is an infectious disease caused by severe acute respiratory syndrome virus coronavirus 2 (SARS-COV-2). Many aspects of its pathology and pathogenesis are not well understood.

MATERIAL AND METHODS

We describe a series of spontaneous air leak cases we found in our coronavirus disease 2019 (COVID-19) positive 1086-patient cohort.

RESULTS

Two out of six patients eventually required mechanical ventilation and succumbed to COVID-19. We presume that acute lung injury leading to SARS-CoV-2 with associated acute respiratory distress syndrome predisposes patients to this complication.

CONCLUSION

This series is presented to highlight the emerging association of COVID-19 with spontaneous air leaks leading to pneumomediastinum, pneumothorax, and subsequent subcutaneous emphysema even in patients who have never received invasive mechanical ventilation and this may be more likely with the institution of high flow nasal cannula.

摘要

背景

2019冠状病毒病是一种由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的传染病。其病理学和发病机制的许多方面尚未完全了解。

材料与方法

我们描述了在我们的1086例2019冠状病毒病(COVID-19)阳性患者队列中发现的一系列自发性气胸病例。

结果

6例患者中有2例最终需要机械通气,并死于COVID-19。我们推测,导致SARS-CoV-2的急性肺损伤及相关急性呼吸窘迫综合征使患者易患此并发症。

结论

本系列病例旨在强调COVID-19与自发性气胸之间新出现的关联,即使从未接受有创机械通气的患者也可能出现气胸、纵隔气肿及随后的皮下气肿,而在使用高流量鼻导管时这种情况可能更易发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a241/8191243/d6114ccfa21f/SJA-15-93-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a241/8191243/d6114ccfa21f/SJA-15-93-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a241/8191243/d6114ccfa21f/SJA-15-93-g001.jpg

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本文引用的文献

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Spontaneous Pneumomediastinum: A Probable Unusual Complication of Coronavirus Disease 2019 (COVID-19) Pneumonia.自发性纵隔气肿:2019冠状病毒病(COVID-19)肺炎可能出现的一种罕见并发症
Korean J Radiol. 2020 May;21(5):627-628. doi: 10.3348/kjr.2020.0281.
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Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19).拯救脓毒症运动:2019 冠状病毒病(COVID-19)危重症成人管理指南。
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Mediastinal Emphysema, Giant Bulla, and Pneumothorax Developed during the Course of COVID-19 Pneumonia.
在 COVID-19 肺炎的病程中发生了纵隔气肿、巨大肺大疱和气胸。
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COVID-19 with spontaneous pneumomediastinum.伴有自发性纵隔气肿的新型冠状病毒肺炎
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