Chirikian David, Awsare Sohun, Fitzgibbon John, Lee Lenora
California Northstate University College of Medicine, 9700 West Taron Drive, Elk Grove, CA, 95757, USA.
Department of Infectious Disease, Kaiser Permanente Sacramento Medical Center, 2025 Morse Avenue, Sacramento, CA, 95825, USA.
IDCases. 2021 Jun 11;25:e01189. doi: 10.1016/j.idcr.2021.e01189. eCollection 2021.
There is a known relationship between bacteremia and colorectal malignancies. is a gram-positive, anaerobic, spore-forming bacterium that can survive the acidic colorectal tumor microenvironment, where it is thought to enter the blood by tumor-mediated epithelial tissue damage. While in circulation, can release exotoxins which may lead to life-threatening sepsis. The patient in this case presented with a mild fever, abdominal pain, and left hand weakness. Imaging of the head and abdomen revealed a right frontal lucency and wall thickening of the ascending colon. Two colonic adenocarcinomas were found and removed via an exploratory laparotomy and right hemicolectomy. The blood culture was positive for . Brain MRI confirmed a right frontal mass concerning for metastasis. Here, we discuss the relationship between colonic cancers and bacteremia.
菌血症与结直肠恶性肿瘤之间存在已知的关联。[细菌名称]是一种革兰氏阳性、厌氧、产芽孢的细菌,它能够在酸性的结直肠肿瘤微环境中存活,据认为它会通过肿瘤介导的上皮组织损伤进入血液。在血液循环过程中,[细菌名称]会释放外毒素,这可能导致危及生命的败血症。该病例中的患者出现低热、腹痛和左手无力症状。头部和腹部影像学检查显示右额叶透亮区以及升结肠壁增厚。通过剖腹探查术和右半结肠切除术发现并切除了两个结肠腺癌。血培养显示[细菌名称]呈阳性。脑部磁共振成像证实右额叶有一个可疑转移瘤。在此,我们讨论结肠癌与菌血症之间的关系。