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弓形虫与精神障碍的关系及其对基于大脑的诊断系统和新型治疗方法的启示:一项研究方案

Relationship between Toxoplasma Gondii and Psychotic Disorders with Implications toward a Brain-based Diagnostic System and Novel Treatment Approaches: A Study Protocol.

作者信息

Raja Dina, Das Shyamanta, Phukan Chimanjita, Talukdar Simanta, Bhandari Samrat Singh, Hazarika Naba Kumar, Bhagabati Dipesh

机构信息

Department of Microbiology, Gauhati Medical College Hospital, Guwahati, Assam, India.

Department of Psychiatry, Gauhati Medical College Hospital, Guwahati, Assam, India.

出版信息

J Adv Med Med Res. 2021;33(13):82-88. doi: 10.9734/JAMMR/2021/v33i1330958. Epub 2021 Jun 8.

Abstract

What role infectious agents play in the causation of psychotic disorders? To investigate this area, we have aimed to investigate the relationship between Toxoplasma gondii and psychotic disorders. A hospital-based cross-sectional study is designed. IgM and IgG antibodies to T. gondii in patients with psychotic disorders will be measured and presented in result. Seropositivity rates will be compared with first-degree relatives and healthy volunteers. Also, types of psychotic disorders and seropositivity rate will be compared. Here, we are presenting the study protocol with implications toward a brain-based diagnostic system and novel treatment approaches.

摘要

感染因子在精神障碍的病因中起什么作用?为了研究这一领域,我们旨在调查弓形虫与精神障碍之间的关系。设计了一项基于医院的横断面研究。将测量精神障碍患者体内针对弓形虫的IgM和IgG抗体,并在结果中呈现。血清阳性率将与一级亲属和健康志愿者进行比较。此外,还将比较精神障碍的类型和血清阳性率。在此,我们展示了该研究方案及其对基于大脑的诊断系统和新型治疗方法的意义。

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