精神分裂症及相关精神病性障碍：初步报告。
Association in and Related Psychotic Disorders: A Primary Report.
作者信息
Raja Dina, Das Shyamanta, Phukan Chimanjita, Talukdar Simanta, Bhandari Samrat S, Singh Sanjay
机构信息
Department of Microbiology, Dhubri Medical College and Hospital, Dhubri, Assam, India.
Department of Psychiatry, Dhubri Medical College and Hospital, Dhubri, Assam, India.
出版信息
East J Psychiatry. 2024 Jan-Jun;24(1):22-23. doi: 10.5005/jp-journals-11001-0075. Epub 2024 Jun 8.
BACKGROUND
Implication of infection in etiology of psychotic disorders is an area of interest.
AIM
We aimed to explore the relationship between and psychotic disorders in a preliminary study.
MATERIALS AND METHODS
immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies were measured in a sample of patients with psychotic disorders, first-degree relatives (FDR), and healthy volunteers (HV) and compared. Data were analyzed by descriptive statistics in the forms of frequency and percentage using Statistical Package for the Social Sciences (SPSS).
RESULTS
Sample size was 10. Men and women were equal. All were from rural background. One patient with psychotic disorder out of the four had anti- IgG antibodies in comparison to none among the three each of the FDR and HV. The patient with positive IgG antibody status had the diagnosis of acute and transient psychotic disorder (ATPD).
CONCLUSION
This pioneering pilot project from this part of the globe highlights a pertinent area for further work in the future in order to have a newer understanding in proper management of psychotic disorder.
背景
感染在精神障碍病因学中的作用是一个备受关注的领域。
目的
在一项初步研究中，我们旨在探讨[具体内容缺失]与精神障碍之间的关系。
材料与方法
对一组精神障碍患者、一级亲属（FDR）和健康志愿者（HV）的样本进行免疫球蛋白M（IgM）和免疫球蛋白G（IgG）抗体检测并比较。使用社会科学统计软件包（SPSS）以频率和百分比的形式通过描述性统计分析数据。
结果
样本量为10。男女数量相等。所有人均来自农村背景。四名精神障碍患者中有一名患者检测出抗IgG抗体，而三名FDR和三名HV中均无此类情况。IgG抗体状态呈阳性的患者被诊断为急性短暂性精神病性障碍（ATPD）。
结论
来自世界这一地区的这个开创性试点项目突出了一个未来值得进一步研究的相关领域，以便在精神障碍的合理管理方面有新的认识。
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