Kashiwagi S, Ikematsu H, Hayashi J, Nomura H, Kajiyama W, Kaji M
First Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Jpn J Med. 1988 May;27(2):177-82. doi: 10.2169/internalmedicine1962.27.177.
From Dec 1, 1985 to Jan 18, 1986, 133 of 379 (35.1%) mainly elderly in-patients at a hospital in Fukuoka City were infected with influenza virus A (H3N2). In 32 of the 133 (24.1%) infected with the virus, pneumonia occurred. The occurrence was significantly higher in man (33.1%) than in women (17.1%) (p less than 0.05), and the same occurrence was found to be higher in bed-ridden patients (32.7%) than in ambulatory patients (17.3%) (p less than 0.05). It was also higher in those age 70 or older (25.4%) than in those 69 years or younger (17.4%), but with no statistical difference. Seven men and one woman, all 70 years old or older, infected with the virus died of pneumonia. The overall case-fatality ratio was 6.0%. Thus, male bed-ridden patients aged 70 years or older are highly vulnerable to pneumonia in case of infection with influenza virus A.
1985年12月1日至1986年1月18日，福冈市一家医院的379名主要为老年住院患者中，有133人（35.1%）感染了甲型流感病毒（H3N2）。在这133名感染病毒的患者中，有32人（24.1%）发生了肺炎。男性的发生率（33.1%）显著高于女性（17.1%）（p<0.05），而且卧床患者的发生率（32.7%）高于非卧床患者（17.3%）（p<0.05）。70岁及以上患者的发生率（25.4%）也高于69岁及以下患者（17.4%），但无统计学差异。7名男性和1名女性，均为70岁及以上，感染病毒后死于肺炎。总体病死率为6.0%。因此，70岁及以上的男性卧床患者在感染甲型流感病毒时极易发生肺炎。
