Department of Neurology, Konkuk University School of Medicine, Chungju.
Department of Neurology, Konyang University College of Medicine, Daejeon, Republic of Korea.
Neurologist. 2021 Jul 6;26(4):153-155. doi: 10.1097/NRL.0000000000000332.
Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) is a rare variation of internuclear ophthalmoplegia associated with bilateral lesions of the medial longitudinal fasciculus.
In this case, the edematous lesions of the ipsilateral midbrain infarction appeared to compress the contralateral medial longitudinal fasciculus, resulting in WEBINO. Treatment of focal cerebral edema caused by ischemic stroke is still under debate. However, in this case, antiedema treatment was implemented to prevent the sequelae of the edematous lesion caused by a midbrain infarction, and a relatively rapid improvement of ocular symptoms was observed.
Herein, we report a rare case of WEBINO caused by a unilateral midbrain infarction in which the patient experienced edema-related neurological deficits. This case provides evidence that early antiedema therapy may benefit patients with similar presentations.
核间眼肌麻痹的双眼 Wall-eyed 变异型（WEBINO）是一种罕见的核间眼肌麻痹变异型，与内侧纵束的双侧病变有关。
在本病例中，同侧中脑梗死的水肿性病变似乎压迫了对侧内侧纵束，导致 WEBINO。针对缺血性卒中引起的局限性脑水肿的治疗仍存在争议。然而，在本病例中，我们实施了抗水肿治疗，以预防中脑梗死引起的水肿性病变的后遗症，并且观察到眼部症状相对较快地改善。
本研究报告了一例由单侧中脑梗死引起的罕见 WEBINO 病例，患者出现了与水肿相关的神经功能缺损。该病例提供了证据表明，早期抗水肿治疗可能对具有类似表现的患者有益。
