Servicio de Neurología, Hospital Universitari Arnau de Vilanova, Lleida, España.
Centro de Atención Primaria Bordeta-Magraners, Lleida, España.
Arch Soc Esp Oftalmol (Engl Ed). 2020 Apr;95(4):205-208. doi: 10.1016/j.oftal.2019.12.012. Epub 2020 Feb 20.
WEBINO (wall-eyed bilateral internuclear ophthalmoplegia) syndrome is characterized by bilateral adduction impairment, nystagmus of the abducting eye, and primary gaze exotropia. We present the case of a 68 year-old man who was initially attended in emergency department with sudden onset diplopia. Neurological exploration revealed WEBINO and gait ataxia. Relevant medical history included liver transplantation and subsequent tacrolimus prescription. Complementary exams revealed ischemic lesion in mesencephalic tegmentum, involving medial longitudinal fasciculus and pretectal area. WEBINO syndrome is unfrequent. Among its etiologies, ischemic and demyelinating are the most frequent. In our case, iatrogenic etiology was also considered. Clinical recognition of this syndrome is required to perform adequate exams in order to reach diagnosis.
WEBINO（双眼内侧核间眼肌麻痹）综合征的特征是双侧内收障碍、外展眼球的眼球震颤和第一眼位外斜视。我们报告了一例 68 岁男性患者，他最初因突发复视就诊于急诊。神经科检查显示 WEBINO 和步态共济失调。相关病史包括肝移植和随后的他克莫司处方。补充检查显示中脑被盖的缺血性病变，累及内侧纵束和视前区。WEBINO 综合征并不常见。在其病因中，缺血性和脱髓鞘性最常见。在我们的病例中，也考虑了医源性病因。需要临床识别这种综合征，以便进行充分的检查以做出诊断。
