Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, California, USA.
Cousins Center for Psychoneuroimmunology, Jane & Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA; Department of Psychiatry and Biobehavioral Sciences, Jane & Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
Sleep Health. 2021 Oct;7(5):638-643. doi: 10.1016/j.sleh.2021.05.004. Epub 2021 Jun 27.
Insufficient sleep and circadian disruption have been linked to immune system dysregulation. The aim of this study was to examine the associations between self-reported sleep duration and work schedule with reports of head and chest colds among adults 18 years and older in the United States.
Associations between self-reported habitual sleep duration and work schedule (regular daytime, regular evening, regular nighttime, rotating, other) with reports head and chest colds in the past 2 weeks were examined using data from the 2010 and 2015 National Health Interview Survey. Adults who slept 7-8 hours or reported a regular daytime work schedule were considered the reference group. Multivariate logistic regressions, incorporating sampling weights, were computed adjusting for sociodemographic and health characteristics.
Analyses revealed in fully adjusted models that compared to 7- 8 hours sleepers, those sleeping 5 or fewer hours were 44% more likely to report a cold (odds ratio [OR] = 1.44, 95% confidence interval [CI] 1.29-1.61) while those sleeping 9 or more hours were 20% more likely (OR = 1.20, 95% CI 1.06-1.36). Participants who reported a rotating work schedule were 20% more likely to report a cold (OR = 1.20, 95% CI 1.07-1.36) than those reporting a regular daytime work schedule.
Short and long sleep duration, as well as a rotating shift work schedule, were associated with increased reports of head and chest colds in a nationally representative sample of US adults. Sleep and circadian function may serve as relevant targets to reduce susceptibility to infectious illness.
睡眠不足和昼夜节律紊乱与免疫系统失调有关。本研究旨在调查美国 18 岁及以上成年人自我报告的睡眠时间和工作时间表与过去 2 周内报告的头和胸部感冒之间的关联。
利用 2010 年和 2015 年全国健康访谈调查的数据，研究了自我报告的习惯性睡眠时间和工作时间表（常规白天、常规晚上、常规夜间、轮班、其他）与过去 2 周内头和胸部感冒报告之间的关联。睡眠时间为 7-8 小时或报告常规白天工作时间表的成年人被视为参考组。采用包含抽样权重的多变量逻辑回归模型，调整了社会人口统计学和健康特征。
在完全调整的模型中分析表明，与 7-8 小时睡眠者相比，睡眠时间为 5 小时或更少的人报告感冒的可能性高 44%（比值比 [OR] = 1.44，95%置信区间 [CI] 1.29-1.61），而睡眠时间为 9 小时或更多的人报告感冒的可能性高 20%（OR = 1.20，95% CI 1.06-1.36）。与报告常规白天工作时间表的参与者相比，报告轮班工作时间表的参与者报告感冒的可能性高 20%（OR = 1.20，95% CI 1.07-1.36）。
在具有全国代表性的美国成年人样本中，短时间和长时间睡眠以及轮班工作时间表与头和胸部感冒报告增加有关。睡眠和昼夜节律功能可能是降低易感性的相关目标。
