Suppr超能文献

智能型肿瘤宁治疗装置对荷肝癌小鼠肿瘤红细胞免疫及肿瘤细胞周期的影响。

Effect of Tumor Red Blood Cell Immunity and Tumor Cell Cycle in Mice Bearing Solid Liver Cancer with Intelligent Cancer Zhongning Therapeutic Apparatus.

机构信息

Institute of Biomedical Engineering, Hangzhou Dianzi University, Hangzhou 310018, Zhejiang, China.

College of Pharmaceutical, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China.

出版信息

J Healthc Eng. 2021 Jun 4;2021:3329800. doi: 10.1155/2021/3329800. eCollection 2021.

Abstract

People's unhealthy lifestyles, especially the number of smoking and passive smoking populations, are increasing year by year and the population is aging. With the development and progress of lung cancer cell and molecular biology, the incidence rate and mortality rate of lung cancer are increasing year by year. The existing tumor biochemotherapy has rapidly developed from preliminary research and animal research to clinical research. The smart cancer Zhongning therapeutic device can induce necrosis and apoptosis of tumor cells. The effect of treating tumors is getting more and more attention. Therefore, this article focuses on the effect of the smart cancer Zhongning therapeutic device on the tumor red blood cells and tumor cell cycle of mice with solid liver cancer. The immunological effects of the drug were discussed. Forty mice were randomly divided into high-dose group, low-dose group, 5-FU group, and model group. The effects of different treatment stages on tumor red blood cell immune function and cell cycle were recorded and evaluated, and the survival rate by multiplying the positive limit method was calculated. The model group is controlled by the exact probability method, and the Pss18.0 system is used to test the hypothesis of survival rate comparison. The experimental results showed that the tumor inhibition rate in this group was 65.8%. Compared with the 5-FU group and model group, the dose group has shown an antitumor effect and had significantly improved the tumor-bearing body's antitumor red blood cell immune function and tumor cell cycle.

摘要

人们不健康的生活方式,尤其是吸烟和被动吸烟人群的数量,逐年增加,人口老龄化。随着肺癌细胞和分子生物学的发展和进步,肺癌的发病率和死亡率逐年上升。现有的肿瘤生物化疗已从初步研究和动物研究迅速发展到临床研究。智能癌症中卫治疗设备可以诱导肿瘤细胞的坏死和凋亡。治疗肿瘤的效果越来越受到关注。因此,本文重点研究智能癌症中卫治疗设备对实体肝癌小鼠肿瘤红细胞和肿瘤细胞周期的影响,并探讨了药物的免疫作用。将 40 只小鼠随机分为高剂量组、低剂量组、5-FU 组和模型组。记录和评估不同治疗阶段对肿瘤红细胞免疫功能和细胞周期的影响,并采用正限法相乘计算生存率。模型组采用确切概率法对照,采用 Pss18.0 系统检验生存率比较的假设。实验结果表明,该组的肿瘤抑制率为 65.8%。与 5-FU 组和模型组相比,剂量组表现出抗肿瘤作用,显著提高了荷瘤机体的抗肿瘤红细胞免疫功能和肿瘤细胞周期。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff10/8203346/cb264d46c2f6/JHE2021-3329800.001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验