Aurilio Caterina, Sansone Pasquale, Paladini Antonella, Barbarisi Manlio, Coppolino Francesco, Pota Vincenzo, Pace Maria Caterina
Department of Women, Child, General and Specialistic Surgery, University of Campania "L. Vanvitelli", 80138 Napoli, Italy.
Department of MESVA, University of L'Aquila, 67100 L'Aquila, Italy.
Life (Basel). 2021 Jun 23;11(7):601. doi: 10.3390/life11070601.
Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is often complicated by severe acute respiratory syndrome. The new coronavirus outbreak started in China in December 2019 and rapidly spread around the world. The high diffusibility of the virus was the reason for the outbreak of the pandemic viral disease, reaching more than 100 million infected people globally by the first three months of 2021. In the various treatments used up to now, the use of antimicrobial drugs for the management, especially of bacterial co-infections, is very frequent in patients admitted to intensive care. In addition, critically ill patients with SARS-CoV-2 infection are subjected to prolonged mechanical ventilation and other therapeutic procedures often responsible for developing hospital co-infections due to multidrug-resistant bacteria. Co-infections contribute to the increase in the morbidity-mortality of viral respiratory infections. We performed this study to review the recent articles published on the antibiotic bacterial resistance and viruses to predict risk factors of coronavirus disease 2019 and to assess the multidrug resistance in patients hospitalized in the COVID-19 area.
2019冠状病毒病(COVID-19)由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起,常并发严重急性呼吸综合征。新型冠状病毒疫情于2019年12月在中国爆发,并迅速蔓延至全球。病毒的高传播性是这场大流行病毒性疾病爆发的原因,截至2021年第一季度,全球感染人数超过1亿。在目前使用的各种治疗方法中,使用抗菌药物进行治疗,尤其是用于治疗细菌合并感染,在入住重症监护病房的患者中非常常见。此外,感染SARS-CoV-2的重症患者需要长时间机械通气和其他治疗程序,这些治疗往往会导致多重耐药菌引起医院内合并感染。合并感染会导致病毒性呼吸道感染的发病率和死亡率上升。我们开展这项研究,以回顾最近发表的关于抗生素细菌耐药性和病毒的文章,预测2019冠状病毒病的危险因素,并评估COVID-19病区住院患者的多重耐药情况。