Su Chen-Ying, Yeh Lung-Kun, Fan Tzu-Wei, Lai Chi-Chun, Fang Hsu-Wei
Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, 1, Sec. 3, Zhongxiao E. Rd., Taipei 10608, Taiwan.
Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, No. 5, Fuxing St., Taoyuan 333, Taiwan.
Polymers (Basel). 2021 Jun 23;13(13):2051. doi: 10.3390/polym13132051.
Feeling comfortable is the greatest concern for contact lens wearers, and it has been suggested that in vivo comfort could be corresponded to the in vitro friction coefficient of contact lenses. How tear albumin could affect the friction coefficient of silicone hydrogel and hydrogel contact lenses was analyzed by sliding a lens against a quartz glass in normal and extremely high concentration of albumin solution. Albumin deposition testing and surface roughness analysis were also conducted. The results showed that the friction coefficient of tested contact lenses did not correspond to both the albumin deposition amount and surface roughness, but we proposed a model of how albumin might act as a lubricant on the surface of some hydrogel and silicone hydrogel contact lenses. In conclusion, albumin provided lubrication for silicone hydrogel contact lenses regardless of albumin concentrations, while albumin only acted as a lubricant for hydrogel contact under normal concentration.
佩戴舒适是隐形眼镜佩戴者最为关心的问题，有人提出，体内舒适度可能与隐形眼镜的体外摩擦系数相关。通过在正常浓度和极高浓度的白蛋白溶液中使镜片与石英玻璃滑动摩擦，分析了泪液白蛋白如何影响硅水凝胶和水凝胶隐形眼镜的摩擦系数。还进行了白蛋白沉积测试和表面粗糙度分析。结果表明，受试隐形眼镜的摩擦系数与白蛋白沉积量和表面粗糙度均不相关，但我们提出了一个模型，说明白蛋白可能如何在某些水凝胶和硅水凝胶隐形眼镜表面起到润滑剂的作用。总之，无论白蛋白浓度如何，白蛋白都为硅水凝胶隐形眼镜提供润滑作用，而在正常浓度下，白蛋白仅对水凝胶隐形眼镜起到润滑作用。
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