Yaghi Nathalie, Yaghi Cesar, Abifadel Marianne, Boulos Christa, Feart Catherine
Department of Nutrition & Dietetics, Faculty of Pharmacy, Saint Joseph University of Beirut, P.O. Box 17-5208 Mar Mikhael, Beirut 1104 2020, Lebanon.
Department of Gastroenterology, Faculty of Medicine, Saint Joseph University of Beirut, P.O. Box 17-5208 Mar Mikhael, Beirut 1104 2020, Lebanon.
Nutrients. 2021 Jun 25;13(7):2188. doi: 10.3390/nu13072188.
Factors associated with frailty, particularly dietary patterns, are not fully understood in Mediterranean countries. This study aimed to investigate the association of data-driven dietary patterns with frailty prevalence in older Lebanese adults. We conducted a cross-sectional national study that included 352 participants above 60 years of age. Sociodemographic and health-related data were collected. Food frequency questionnaires were used to elaborate dietary patterns via the K-mean cluster analysis method. Frailty that accounted for 15% of the sample was twice as much in women (20%) than men (10%). Identified dietary patterns included a Westernized-type dietary pattern (WDP), a high intake/Mediterranean-type dietary pattern (HI-MEDDP), and a moderate intake/Mediterranean-type dietary pattern (MOD-MEDDP). In the multivariate analysis, age, waist to height ratio, polypharmacy, age-related conditions, and WDP were independently associated with frailty. In comparison to MOD-MEDDP, and after adjusting for covariates, adopting a WDP was strongly associated with a higher frailty prevalence in men (OR = 6.63, 95% (CI) (1.82-24.21) and in women (OR = 11.54, 95% (CI) (2.02-65.85). In conclusion, MOD-MEDDP was associated with the least prevalence of frailty, and WDP had the strongest association with frailty in this sample. In the Mediterranean sample, a diet far from the traditional one appears as the key deleterious determinant of frailty.
在地中海国家，与衰弱相关的因素，尤其是饮食模式，尚未得到充分了解。本研究旨在调查数据驱动的饮食模式与黎巴嫩老年成年人衰弱患病率之间的关联。我们开展了一项全国性横断面研究，纳入了352名60岁以上的参与者。收集了社会人口统计学和健康相关数据。通过食物频率问卷，采用K均值聚类分析方法来确定饮食模式。占样本15%的衰弱者中，女性（20%）是男性（10%）的两倍。确定的饮食模式包括西化型饮食模式（WDP）、高摄入量/地中海型饮食模式（HI-MEDDP）和中等摄入量/地中海型饮食模式（MOD-MEDDP）。在多变量分析中，年龄、腰高比、多重用药、与年龄相关的疾病以及WDP与衰弱独立相关。与MOD-MEDDP相比，在调整协变量后，采用WDP与男性更高的衰弱患病率（OR = 6.63，95%（CI）（1.82 - 24.21））和女性更高的衰弱患病率（OR = 11.54，95%（CI）（2.02 - 65.85））密切相关。总之，在本样本中，MOD-MEDDP与最低的衰弱患病率相关，而WDP与衰弱的关联最强。在地中海样本中，远离传统的饮食似乎是衰弱的关键有害决定因素。
