Gąsior Gabriela, Szczepański Jonasz, Radtke Aleksandra
Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland.
Materials (Basel). 2021 Jun 18;14(12):3381. doi: 10.3390/ma14123381.
Iron, while attracting less attention than magnesium and zinc, is still one of the best candidates for biodegradable metal stents thanks its biocompatibility, great elastic moduli and high strength. Due to the low corrosion rate, and thus slow biodegradation, iron stents have still not been put into use. While these problems have still not been fully resolved, many studies have been published that propose different approaches to the issues. This brief overview report summarises the latest developments in the field of biodegradable iron-based stents and presents some techniques that can accelerate their biocorrosion rate. Basic data related to iron metabolism and its biocompatibility, the mechanism of the corrosion process, as well as a critical look at the rate of degradation of iron-based systems obtained by several different methods are included. All this illustrates as the title says, what was done within the topic of biodegradable iron-based materials and what more can be done.
与镁和锌相比，铁虽然较少受到关注，但由于其生物相容性、良好的弹性模量和高强度，仍是可生物降解金属支架的最佳候选材料之一。由于腐蚀速率低，因此生物降解缓慢，铁支架仍未投入使用。虽然这些问题尚未得到充分解决，但已经发表了许多研究，提出了针对这些问题的不同方法。这份简要综述报告总结了可生物降解铁基支架领域的最新进展，并介绍了一些可以加速其生物腐蚀速率的技术。其中包括与铁代谢及其生物相容性相关的基础数据、腐蚀过程的机制，以及对通过几种不同方法获得的铁基系统降解速率的批判性审视。正如标题所说，所有这些都说明了在可生物降解铁基材料这一主题内已经做了什么，以及还可以做什么。
