Department of Psychiatry, Bahir Dar University, Bahir Dar, Ethiopia
Department of Psychiatry, Bahir Dar University, Bahir Dar, Ethiopia.
BMJ Open. 2021 Jul 1;11(7):e048931. doi: 10.1136/bmjopen-2021-048931.
The objective of this study was to compare depressive symptoms among people with HIV/AIDS and the general population sample. We also assessed the factors associated with depressive symptoms.
A comparative cross-sectional study was conducted.
Antiretroviral therapy clinics in three primary healthcare facilities and semi-urban area in Northwest Ethiopia.
A total of 1115 participants (558 people with HIV/AIDS and 557 comparison group) aged 18 years and above were recruited. A total of 1026 participants (530 people with HIV/AIDS and 496 comparison group) completed the interview. We excluded people with known HIV-positive status from the comparison group.
Patient Health Questionnaire (PHQ-9) was used to assess depressive symptoms. The proportion of depressive symptoms was compared between samples of the general population and people with HIV/AIDS using χ statistics. Multivariable logistic regression analysis was done to examine the associated factors.
The overall prevalence of depressive symptoms was 13.3% (11.2%-15.4%). The prevalence was significantly higher in people with HIV/AIDS compared with the community sample (16.6% vs 12.3%), p=0.001. The difference was also significant in the multivariable logistic regression (OR 1.7). For the overall sample, depressive symptoms were significantly associated with older age, being single, divorced/widowed marital status, and poor social support.
Depressive symptoms were higher in people with HIV/AIDS compared with the general population. It is necessary to include mental healthcare and screening for depression in routine HIV/AIDS care.
本研究旨在比较 HIV/AIDS 患者和一般人群的抑郁症状。我们还评估了与抑郁症状相关的因素。
这是一项横断面比较研究。
在埃塞俄比亚西北部的三家基层医疗保健机构和半城市地区的抗逆转录病毒治疗诊所。
共招募了 1115 名参与者(558 名 HIV/AIDS 患者和 557 名对照组),年龄在 18 岁及以上。共有 1026 名参与者(530 名 HIV/AIDS 患者和 496 名对照组)完成了访谈。我们从对照组中排除了已知 HIV 阳性的人。
采用患者健康问卷(PHQ-9)评估抑郁症状。使用 χ 统计比较一般人群样本和 HIV/AIDS 患者样本中抑郁症状的比例。采用多变量逻辑回归分析来检查相关因素。
总体抑郁症状的患病率为 13.3%(11.2%-15.4%)。HIV/AIDS 患者的患病率明显高于社区样本(16.6%比 12.3%),p=0.001。多变量逻辑回归分析也显示出显著差异(OR 1.7)。对于总体样本,抑郁症状与年龄较大、单身、离婚/丧偶的婚姻状况和较差的社会支持显著相关。
HIV/AIDS 患者的抑郁症状高于一般人群。有必要在常规 HIV/AIDS 护理中纳入心理健康保健和抑郁筛查。