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临床疗效芦荟牙膏对牙周参数的牙龈炎患者随机对照单盲临床试验。

Clinical Efficacy of Aloe Vera Toothpaste on Periodontal Parameters of Patients with Gingivitis-A Randomized, Controlled, Single-masked Clinical Trial.

机构信息

Department of Periodontics Sciences, Islamic Azad University, Tehran, Iran.

Department of Periodontics, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran, Phone: +989124040359, e-mail:

出版信息

J Contemp Dent Pract. 2021 Mar 1;22(3):242-247.

PMID:34210922
Abstract

AIM AND OBJECTIVE

This study aims to assess the effects of aloe vera toothpaste on dental plaques and gingivitis.

MATERIALS AND METHODS

This single-center, single-blind, randomized, two-period crossover study was performed on 20 dental students with a mean age of 24.5 ± 4 years with gingivitis. Subjects were randomly assigned to two groups ( = 10). After 14 days of trial period, plaque index (PI) and gingival index (GI) were assessed for each group. The first group used aloe vera toothpaste for 30 days and then their PI and GI were recorded. A 2-week washout period was allowed and then the subjects used fluoride toothpaste for the next 30 days and underwent PI and GI assessment again. This order was reversed in group 2.

RESULTS

Toothpaste-containing aloe vera showed no significant improvement in the GI and PI scores as compared with a fluoride-containing dentifrice. PI was 2.14 ± 1.3 at baseline and 1.84 ± 1.02 in 30 days ( <0.098). GI was 0.62 ± 0.74 at baseline and 0.25 ± 0.46 at 30 days ( <0.068). During the trial, no side effects were seen due to the use of aloe vera or fluoride toothpaste.

CONCLUSION

The effect of aloe vera toothpaste on PI and GI was similar to that of fluoride toothpaste and it seems that this toothpaste can be used as an alternative to a chemical toothpaste.

CLINICAL SIGNIFICANCE

The use of an aloe vera toothpaste in improving the progression of gingivitis can be evaluated.

摘要

目的和目标

本研究旨在评估芦荟牙膏对牙菌斑和牙龈炎的影响。

材料和方法

这是一项单中心、单盲、随机、两周期交叉研究,纳入了 20 名平均年龄为 24.5 ± 4 岁、患有牙龈炎的牙科学生。受试者被随机分为两组(n = 10)。经过 14 天的试验期后,评估每组的菌斑指数(PI)和牙龈指数(GI)。第一组使用芦荟牙膏 30 天,然后记录其 PI 和 GI。允许 2 周的洗脱期,然后受试者使用含氟牙膏 30 天,再次评估 PI 和 GI。在第二组中,这个顺序被颠倒了。

结果

与含氟牙膏相比,含芦荟的牙膏在 GI 和 PI 评分方面没有显著改善。PI 在基线时为 2.14 ± 1.3,30 天时为 1.84 ± 1.02(<0.098)。GI 在基线时为 0.62 ± 0.74,30 天时为 0.25 ± 0.46(<0.068)。在试验期间,由于使用芦荟或含氟牙膏,没有观察到任何副作用。

结论

芦荟牙膏对 PI 和 GI 的影响与含氟牙膏相似,因此这种牙膏可以作为化学牙膏的替代品。

临床意义

可以评估使用芦荟牙膏改善牙龈炎进展的效果。

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