Hao Qinjian, Wang Dahai, Xie Min, Tang Yiguo, Dou Yikai, Zhu Ling, Wu Yulu, Dai Minhan, Wu Hongmei, Wang Qiang
The Center of Gerontology and Geriatrics, West China Hospital of Sichuan University, Chengdu, China.
Department of Psychiatry, Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region, Chengdu, China.
Front Psychiatry. 2021 Jun 15;12:567381. doi: 10.3389/fpsyt.2021.567381. eCollection 2021.
The purpose of this meta-analysis was to summarize the prevalence and risk factors of mental health problems among healthcare workers during the COVID-19 pandemic. We applied an optimized search strategy across the PubMed, EMBASE, Scopus, PsycINFO, and four Chinese databases, with hand searching supplemented to identify relevant surveys. Studies were eligible for inclusion if they were published in peer-reviewed literature and used a validated method to assess the prevalence and risk factors of mental health problems among healthcare workers during the COVID-19 pandemic. Heterogeneity was quantified using statistics and the statistics. The potential causes of heterogeneity were investigated using subgroup analysis and meta-regression analysis. Sensitivity analysis was performed to examine the robustness of the results. We pooled and analyzed data from 20 studies comprising 10,886 healthcare workers. The prevalence of depression, anxiety, insomnia, post-traumatic stress symptoms, phobia, obsessive-compulsive symptoms, and somatization symptoms was 24.1, 28.6, 44.1, 25.6, 35.0, 16.2, and 10.7%, respectively. Female and nurses had a high prevalence of depression and anxiety. Frontline healthcare workers had a higher prevalence of anxiety and a lower prevalence of depression than the those in the second-line. Furthermore, the proportion of moderate-severe depression and anxiety is higher in the frontline. Additionally, four studies reported on risk factors of mental health problems. In this systematic review, healthcare workers have a relatively high prevalence of depression, anxiety, insomnia, post-traumatic stress symptoms, phobia, obsessive-compulsive symptoms, and somatization symptoms during the COVID-19 pandemic, and focus should be on the healthcare workers at high risk of mental problems. Mental health problems in healthcare workers should be taken seriously, and timely screening and appropriate intervention for the high-risk group are highly recommended. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020179189.
本荟萃分析的目的是总结新冠疫情期间医护人员心理健康问题的患病率及风险因素。我们在PubMed、EMBASE、Scopus、PsycINFO以及四个中文数据库中应用了优化的检索策略，并辅以手工检索以识别相关调查。若研究发表于同行评审文献，且使用经过验证的方法评估新冠疫情期间医护人员心理健康问题的患病率及风险因素，则符合纳入标准。使用 统计量和 统计量对异质性进行量化。采用亚组分析和元回归分析研究异质性的潜在原因。进行敏感性分析以检验结果的稳健性。我们汇总并分析了来自20项研究的数据，这些研究涵盖10,886名医护人员。抑郁、焦虑、失眠、创伤后应激症状、恐惧症、强迫症状和躯体化症状的患病率分别为24.1%、28.6%、44.1%、25.6%、35.0%、16.2%和10.7%。女性和护士的抑郁和焦虑患病率较高。一线医护人员的焦虑患病率较高，抑郁患病率低于二线医护人员。此外，一线医护人员中重度抑郁和焦虑的比例更高。另外，四项研究报告了心理健康问题的风险因素。在本系统评价中，新冠疫情期间医护人员的抑郁、焦虑、失眠、创伤后应激症状、恐惧症、强迫症状和躯体化症状的患病率相对较高，应关注存在心理问题高风险的医护人员。医护人员的心理健康问题应得到重视，强烈建议对高风险群体进行及时筛查和适当干预。https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020179189
