Gupta Aarzoo, Garg Ishan, Iqbal Abbas, Talpur Abdul Subhan, Mañego Alyanna Marie B, Kavuri Rama Kalyani, Bachani Parkash, Naz Sidra, Iqbal Zoya Qamar
Internal Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, Faridabad, IND.
Clinical Medicine, Ross University School of Medicine, Bridgetown, BRB.
Cureus. 2021 May 28;13(5):e15304. doi: 10.7759/cureus.15304.
Reverse transcription-polymerase chain reaction (RT-PCR) and chest X-ray (CXR) are commonly used techniques for diagnosing and assessing prognosis in patients with coronavirus disease-2019 (COVID-19). This study aims to highlight the long-term radiological findings observed on CXR after recovery, in patients with COVID-19. This will help identify patients suffering from long-term consequences of COVID-19 and help them provide adequate care.
This study was conducted in the COVID-19 unit of a tertiary care hospital, Pakistan from August 2020 to February 2021. CXR of patients who were being discharged after negative PCR was done. Participants with positive X-ray findings, which included consolidation, reticular thickening, ground-glass opacities (GGO), pulmonary nodules, and pleural effusions, were enrolled in the study after getting informed consent. All findings were recorded in a self-structured questionnaire. Participants were scheduled to come for follow-up on day 30 after their initial CXR, where their CXR was repeated.
Our results showed that n=429 (60.2%) participants had positive CXR at the time of discharge. After 30 days, n=371 participants returned for a follow-up X-ray. Out of the 371 participants, after 30 days, 123 participants still had positive CXR. Fatigue (41.4%) was the common symptom after 30 days. The most common finding was consolidation (82.1%), followed by reticular thickening (23.5%) on day 30.
In this study, although most of the patients completely recovered serologically from COVID-19, they still had radiological findings in their chest X-rays. Radiological findings are especially important in predicting the clinical course of the disease and may be used to monitor long-term complications.
逆转录聚合酶链反应(RT-PCR)和胸部X线检查(CXR)是诊断和评估2019冠状病毒病(COVID-19)患者预后的常用技术。本研究旨在强调COVID-19患者康复后胸部X线检查观察到的长期影像学表现。这将有助于识别患有COVID-19长期后果的患者,并帮助为他们提供充分的护理。
本研究于2020年8月至2021年2月在巴基斯坦一家三级护理医院的COVID-19病房进行。对PCR检测呈阴性后出院的患者进行胸部X线检查。胸部X线检查结果呈阳性(包括实变、网状增厚、磨玻璃影(GGO)、肺结节和胸腔积液)的参与者在获得知情同意后纳入研究。所有结果均记录在一份自行编制的问卷中。参与者被安排在首次胸部X线检查后第30天前来进行随访,届时重复进行胸部X线检查。
我们的结果显示,429名(60.2%)参与者出院时胸部X线检查结果呈阳性。30天后,371名参与者返回进行随访胸部X线检查。在这371名参与者中,30天后,123名参与者的胸部X线检查结果仍为阳性。疲劳(41.4%)是30天后最常见的症状。第30天最常见的表现是实变(82.1%),其次是网状增厚(23.5%)。
在本研究中,尽管大多数患者在血清学上已从COVID-19中完全康复,但他们的胸部X线检查仍有影像学表现。影像学表现对于预测疾病的临床进程尤为重要,可用于监测长期并发症。