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小脑弥漫性胶质瘤，特殊类型术中挤压细胞学检查。

Intraoperative squash Cytology of diffuse glioma not otherwise specified, of the Cerebellum.

机构信息

UNIVERSITY OF CRETE, GREECE, MEDICAL FACULTY..

MD, Ph.D.

出版信息

Acta Biomed. 2021 Jul 1;92(3):e2021108. doi: 10.23750/abm.v92i3.10392.

DOI:10.23750/abm.v92i3.10392
PMID:34212924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8343735/
Abstract

OBJECTIVE

Diffuse glioma arises anywhere in the CNS, but most frequent in the cerebral hemispheres. The tumor tends to be seen in children and in younger adults aged 20-30. We report one such case in an older female patient presenting the intraoperative cytology of the tumor.

CASE REPORT

A 48-year-old female was diagnosed by MRI with a tumor of cerebellum. Cytologic material was obtained during the resection of the tumor and diagnosed cytologically as glioma.

CONCLUSION

This case is presented to focus the ability of the intraoperative cytology in diagnosis of the glioma, using immunocytology and confirmed by histo- immunohistology.

摘要

目的

弥漫性神经胶质瘤可发生于中枢神经系统的任何部位，但最常见于大脑半球。该肿瘤多见于儿童和 20-30 岁的年轻成年人。我们报告了一例发生在老年女性患者中的此类病例，该患者在手术中对肿瘤进行了细胞学检查。

病例报告

一名 48 岁女性因 MRI 检查诊断为小脑肿瘤。在切除肿瘤期间获得了细胞学标本，并通过细胞学诊断为神经胶质瘤。

结论

本病例旨在强调术中细胞学检查在使用免疫细胞化学方法诊断神经胶质瘤方面的能力，并通过组织免疫组织化学方法得到证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf6/8343735/6d5e76f2dca9/ACTA-93-108-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf6/8343735/e5662cfa2e25/ACTA-93-108-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf6/8343735/0078a175f7fe/ACTA-93-108-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf6/8343735/a094da9a53f9/ACTA-93-108-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf6/8343735/6d5e76f2dca9/ACTA-93-108-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf6/8343735/e5662cfa2e25/ACTA-93-108-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf6/8343735/0078a175f7fe/ACTA-93-108-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf6/8343735/a094da9a53f9/ACTA-93-108-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf6/8343735/6d5e76f2dca9/ACTA-93-108-g004.jpg

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本文引用的文献

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Rapid intraoperative immunocytochemistry of central nervous system tumors.中枢神经系统肿瘤的快速术中免疫细胞化学
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Astrocytoma progression scoring system based on the WHO 2016 criteria.基于 WHO 2016 标准的星形细胞瘤进展评分系统。
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Errors, limitations, and pitfalls in the diagnosis of central and peripheral nervous system lesions in intraoperative cytology and frozen sections.术中细胞学检查及冰冻切片诊断中枢和周围神经系统病变中的错误、局限性及陷阱
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Intraoperative diagnosis of central nervous system lesions: Comparison of squash smear, touch imprint, and frozen section.中枢神经系统病变的术中诊断：压片涂片、触片印片与冰冻切片的比较。
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Rapid immunocytochemistry based on alternating current electric field using squash smear preparation of central nervous system tumors.基于交变电场的快速免疫细胞化学法在中枢神经系统肿瘤压片标本制备中的应用
Brain Tumor Pathol. 2016 Jan;33(1):13-8. doi: 10.1007/s10014-015-0238-0. Epub 2015 Nov 6.
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A Comparative Study of Histopathology of Astrocytomas with Intraoperative Cytology with Special Reference to MIB-1 Labelling Index.星形细胞瘤组织病理学与术中细胞学的比较研究：特别参考MIB-1标记指数
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