Institute of Bio-Sensing Technology, University of the West of England, Frenchay Campus, Bristol, BS16 1QY, UK.
J Clin Monit Comput. 2022 Apr;36(2):315-323. doi: 10.1007/s10877-021-00738-5. Epub 2021 Jul 2.
This paper presents a review of established and emerging methods for detecting and quantifying the intravenous anaesthetic propofol in solution. There is growing evidence of numerous advantages of total intravenous anaesthesia using propofol compared to conventional volatile-based anaesthesia, both in terms of patient outcomes and environmental impact. However, volatile-based anaesthesia still accounts for the vast majority of administered general anaesthetics, largely due to a lack of techniques for real-time monitoring of patient blood propofol concentration. Herein, propofol detection techniques that have been developed to date are reviewed alongside a discussion of remaining challenges.
本文综述了已建立和新兴的检测和定量静脉麻醉药异丙酚溶液的方法。越来越多的证据表明，与传统的挥发性麻醉相比，使用异丙酚的全静脉麻醉在患者结局和环境影响方面具有许多优势。然而，由于缺乏实时监测患者血液中异丙酚浓度的技术，基于挥发性的麻醉仍占大多数全身麻醉的应用，本文综述了迄今为止开发的异丙酚检测技术，并讨论了尚存的挑战。
