Kahn Justine M, Beauchemin Melissa
1Division of Pediatric Hematology/Oncology/Stem Cell Transplantation, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY.
J Natl Compr Canc Netw. 2021 Jun 30;19(6):765-769. doi: 10.6004/jnccn.2021.7048.
Despite extraordinary strides in cancer therapy over the past 30 years, racial/ethnic, socioeconomic, and age-related survival disparities persist. Hodgkin lymphoma offers an excellent paradigm to understand these disparities because successful approaches are well established in both the up-front and relapsed treatment settings. The following review, which accompanies the 2021 NCCN Guidelines for Pediatric Hodgkin Lymphoma, suggests that systemic inequities in cancer care disproportionately affect minority and low-income children, adolescents, and young adults, and directly contribute to observed disparities in cancer-related outcomes. It proposes that the first step toward reducing disparities is large-scale dissemination of guidelines, because equity is best achieved when treatment approaches are clear, comprehensive, and standardized across all clinical practice settings.
尽管在过去30年里癌症治疗取得了非凡进展，但种族/族裔、社会经济和与年龄相关的生存差异依然存在。霍奇金淋巴瘤为理解这些差异提供了一个极佳的范例，因为无论是在初始治疗还是复发治疗环境中，成功的治疗方法都已确立。以下这篇随2021年《NCCN儿童霍奇金淋巴瘤指南》一同发表的综述表明，癌症治疗中的系统性不平等对少数族裔和低收入儿童、青少年及青年成年人的影响尤为严重，并直接导致了在癌症相关结局方面观察到的差异。该综述提出，减少差异的第一步是大规模传播指南，因为当治疗方法在所有临床实践环境中清晰、全面且标准化时，才能最好地实现公平。
