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多层面分析在埃塞俄比亚,产前、产时和产后期间影响 PMTCT 服务利用的决定因素。

A multilevel analysis of determinants of PMTCT service utilisation among women during the antepartum, intrapartum and postpartum period in Ethiopia.

机构信息

Department of Health Systems and Policy, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

出版信息

BMC Pregnancy Childbirth. 2021 Jul 3;21(1):483. doi: 10.1186/s12884-021-03896-1.

Abstract

BACKGROUND

Mother-to-child transmission (MTCT) is the largest source of HIV infection in children below the age of 15 years, and more than 90% of pediatric HIV are infected through mother to child transmission. Without treatment, one-half of those infected children will die before the age of 2 years. Despite this, there is limited evidence on PMTCT and its determinants. Therefore, this study aimed to determine the factors affecting the PMTCT service utilisation in Ethiopia.

METHODS

A two-stage stratified sampling technique was used to identify 4081 women from 2016 Ethiopian Demographic and Health Survey (EDHS). A multilevel mixed-effect binary logistic regression analysis was used to identify the individual and community level factors associated with PMTCT services utilisation. In the final model, a p-value of < 0.05 and Adjusted Odds Ratio (AOR) with 95% confidence interval (CI) were used to declare statistically significant factors with the utilisation.

RESULTS

Overall, 21.9% (95% CI, 20.6-23.2) of the women were utilized PMTCT services. Educational status; primary (AOR: 1.65, 95% CI: 1.27-2.13), secondary (AOR: 1.52, 95% CI: 1.03-2.24) and higher school (AOR: 2.48, 95% CI: 1.45-4.22), poorer (AOR: 1.62, 95% CI: 1.12-2.37), middle (AOR: 1.82, 95% CI: 1.10-3.02), richer (AOR: 2.44, 95% CI: 1.42-4.21) and richest (AOR: 4.45, 95% CI: 2.43-8.14) wealth status and orthodox religion follower (AOR: 1.62, 95% CI: 1.22-2.16) were the individual level factors. Moreover, having basic (AOR: 1.66, 95% CI: 1.34-2.06) and comprehensive (AOR: 1.73, 95% CI: 1.38-2.18) knowledge on HIV prevention methods, having knowledge on MTCT of HIV (AOR: 2.69, 95% CI: 2.16-3.36) were also factors at individual level. Whereas, rural residence (AOR: 0.52, 95% CI: 0.32-0.85) was the community level factors that affects the utilization.

CONCLUSIONS

Less than one-fourth of the mothers had utilised the PMTCT services in Ethiopia. To increase the utilisation of the services, the health care providers should give emphases on counselling, awareness creation, and strengthen the existing frontline integrated health care services in the country.

摘要

背景

母婴传播(MTCT)是 15 岁以下儿童感染艾滋病毒的最大来源,超过 90%的儿科艾滋病毒感染是通过母婴传播的。如果不进行治疗,一半感染的儿童将在 2 岁之前死亡。尽管如此,关于 PMTCT 及其决定因素的证据有限。因此,本研究旨在确定影响埃塞俄比亚 PMTCT 服务利用的因素。

方法

采用两阶段分层抽样技术,从 2016 年埃塞俄比亚人口与健康调查(EDHS)中抽取 4081 名妇女。采用多水平混合效应二项逻辑回归分析确定与 PMTCT 服务利用相关的个体和社区水平因素。在最终模型中,使用 p 值<0.05 和调整后的优势比(AOR)和 95%置信区间(CI)来确定与利用相关的具有统计学意义的因素。

结果

总体而言,21.9%(95%CI,20.6-23.2)的妇女利用了 PMTCT 服务。教育程度;小学(AOR:1.65,95%CI:1.27-2.13)、中学(AOR:1.52,95%CI:1.03-2.24)和高等学校(AOR:2.48,95%CI:1.45-4.22)、较贫穷(AOR:1.62,95%CI:1.12-2.37)、中等(AOR:1.82,95%CI:1.10-3.02)、较富裕(AOR:2.44,95%CI:1.42-4.21)和最富裕(AOR:4.45,95%CI:2.43-8.14)的财富状况和东正教信徒(AOR:1.62,95%CI:1.22-2.16)是个体水平的因素。此外,具有基本(AOR:1.66,95%CI:1.34-2.06)和综合(AOR:1.73,95%CI:1.38-2.18)艾滋病毒预防方法知识、具有艾滋病毒母婴传播知识(AOR:2.69,95%CI:2.16-3.36)也是个体水平的因素。而农村居住(AOR:0.52,95%CI:0.32-0.85)是影响利用的社区水平因素。

结论

埃塞俄比亚不到四分之一的母亲利用了 PMTCT 服务。为了提高服务的利用率,医疗保健提供者应重视咨询、提高认识,并加强该国现有的前线综合医疗保健服务。

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Pediatric AIDS in the elimination agenda.儿科艾滋病消除议程。
PLoS Med. 2013 Aug;10(8):e1001503. doi: 10.1371/journal.pmed.1001503. Epub 2013 Aug 27.

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