Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan.
Faculty of Pharmacy & Medical Sciences, University of Petra, Amman, Jordan.
J Appl Microbiol. 2022 Jan;132(1):41-58. doi: 10.1111/jam.15202. Epub 2021 Jul 26.
Chitosan is an abundant organic polysaccharide, which can be relatively easily obtained by chemical modification of animal or fungal source materials. Chitosan and its derivatives have been shown to exhibit direct antiviral activity, to be useful vaccine adjuvants and to have potential anti-SARS-CoV-2 activity. This thorough and timely review looks at the recent history of investigations into the role of chitosan and its derivatives as an antiviral agent and proposes a future application in the treatment of endemic SARS-CoV-2.
壳聚糖是一种丰富的有机多糖，可以通过对动物或真菌源材料进行化学修饰相对容易地获得。壳聚糖及其衍生物已被证明具有直接的抗病毒活性，可用作有效的疫苗佐剂，并具有抗 SARS-CoV-2 的潜力。这篇全面及时的综述回顾了近期关于壳聚糖及其衍生物作为抗病毒剂作用的研究，并提出了其在治疗地方性 SARS-CoV-2 方面的未来应用。
