Zu D L, Wang X H, Wang J B, Zhuge Y
Cardiology Department, Quzhou People's Hospital, Quzhou 324000, China.
Kaihua County Yinken Rural Hospitals, Quzhou 324309, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2021 Jun 20;39(6):434-437. doi: 10.3760/cma.j.cn121094-20200229-00096.
To assess the health-related quality of life in the agricultural workers with schistosomiasis liver fibrosis using Europe Health-Related Quality of Life Questionnaire 5 Dimensions (EQ-5D) . From January to December 2019, a cross sectional study was applied to 3507 agricultural workers at a township, Kaihua County, Zhejiang Province, of which 424 agricultural workers with schistosomiasis liver fibrosis as objective group and of which 3083 agricultural workers without schistosomiasis liver fibrosis as the control group whom were respectively evaluated by the EQ-5D scale. At the same time, aspartate aminotransferase (AST) and platelet (PLT) ratio index (APRI) was calculated, and B-type ultrasound was used to test the degree of liver fibrosis among two groups. There were 424 patients in the objective group, aged (66.29±7.21) years, and 3083 person in the control group, aged (65.98±14.81) years. The APRI scores between the control group and the objective group were (0.74±0.51) points and (1.04±0.53) points, respectively (<0.01) . The total score of 5 items of EQ-5D was (6.86±2.21) points and (7.88±2.71) points, respectively, in the objective group had 375 cases of liver fibrosis grade I and 49 cases of liver fibrosis grade Ⅱ, which were significantly higher than that of the control group[ (5.50±1.17) points] (<0.01) . Among the respondents, EQ-VAS score was negative correlated with EQ-5D scores (r=-0.616, <0.01) . The health-related quality of life of agricultural workers with schistosomiasis liver fibrosis at a township, Quzhou City Kaihua County decreased compared with the control group.
采用欧洲五维健康量表（EQ - 5D）评估血吸虫病肝纤维化农业劳动者的健康相关生活质量。2019年1月至12月，对浙江省开化县某乡镇的3507名农业劳动者进行横断面研究，其中424名患有血吸虫病肝纤维化的农业劳动者作为观察组，3083名未患血吸虫病肝纤维化的农业劳动者作为对照组，分别采用EQ - 5D量表进行评估。同时，计算天门冬氨酸氨基转移酶（AST）与血小板（PLT）比值指数（APRI），并采用B型超声检测两组肝纤维化程度。观察组424例，年龄（66.29±7.21）岁，对照组3083例，年龄（65.98±14.81）岁。对照组与观察组的APRI评分分别为（0.74±0.51）分和（1.04±0.53）分（P<0.01）。EQ - 5D量表5项总分观察组为（6.86±2.21）分，对照组为（7.88±2.71）分，观察组中肝纤维化Ⅰ级375例、Ⅱ级49例，均显著高于对照组[（5.50±1.17）分]（P<0.01）。在研究对象中，EQ - VAS评分与EQ - 5D评分呈负相关（r=-0.616，P<0.01）。衢州市开化县某乡镇血吸虫病肝纤维化农业劳动者的健康相关生活质量低于对照组。
