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1型糖尿病的胰腺移植:胰岛细胞移植的新作用。

Pancreas transplant in type 1 diabetes mellitus: the emerging role of islet cell transplant.

作者信息

Kochar Inderpal Singh, Jain Rakhi

机构信息

Department of Pediatric and Adolescent Endocrinology, Indraprastha Apollo Hospital, New Delhi, India.

出版信息

Ann Pediatr Endocrinol Metab. 2021 Jun;26(2):86-91. doi: 10.6065/apem.2142012.006. Epub 2021 Jun 30.

Abstract

Pancreas transplant, both whole pancreas and islet cell, is a known therapeutic option for treatment of type 1 diabetes mellitus. Islet cell transplant began as an experimental therapy but is emerging to be quite beneficial due to less surgical risk and fewer complications. It is also considered a promising option in pediatric patients. In this review the authors discuss the indications, procedure, and benefits of islet cell transplant along with newer strategies for improving outcomes.

摘要

胰腺移植,包括全胰腺移植和胰岛细胞移植,是治疗1型糖尿病的一种已知治疗选择。胰岛细胞移植最初是一种实验性疗法,但由于手术风险较低和并发症较少,正逐渐显示出相当大的益处。它也被认为是儿科患者的一种有前景的选择。在这篇综述中,作者讨论了胰岛细胞移植的适应症、手术过程、益处以及改善治疗效果的新策略。

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本文引用的文献

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Stem cells: past, present, and future.干细胞:过去、现在和未来。
Stem Cell Res Ther. 2019 Feb 26;10(1):68. doi: 10.1186/s13287-019-1165-5.
2
Current state and future evolution of pancreatic islet transplantation.胰岛移植的现状与未来发展
Ann Gastroenterol Surg. 2018 Oct 8;3(1):34-42. doi: 10.1002/ags3.12214. eCollection 2019 Jan.
4
The Future of Islet Transplantation Is Now.胰岛移植的未来已来。
Front Med (Lausanne). 2018 Jul 13;5:202. doi: 10.3389/fmed.2018.00202. eCollection 2018.
6
Clinical pancreatic islet transplantation.临床胰腺胰岛移植。
Nat Rev Endocrinol. 2017 May;13(5):268-277. doi: 10.1038/nrendo.2016.178. Epub 2016 Nov 11.
9
Advances in pancreas transplantation.胰腺移植的进展。
J R Soc Med. 2016 Apr;109(4):141-6. doi: 10.1177/0141076816636369.

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