Kochar Inderpal Singh, Jain Rakhi
Department of Pediatric and Adolescent Endocrinology, Indraprastha Apollo Hospital, New Delhi, India.
Ann Pediatr Endocrinol Metab. 2021 Jun;26(2):86-91. doi: 10.6065/apem.2142012.006. Epub 2021 Jun 30.
Pancreas transplant, both whole pancreas and islet cell, is a known therapeutic option for treatment of type 1 diabetes mellitus. Islet cell transplant began as an experimental therapy but is emerging to be quite beneficial due to less surgical risk and fewer complications. It is also considered a promising option in pediatric patients. In this review the authors discuss the indications, procedure, and benefits of islet cell transplant along with newer strategies for improving outcomes.
胰腺移植,包括全胰腺移植和胰岛细胞移植,是治疗1型糖尿病的一种已知治疗选择。胰岛细胞移植最初是一种实验性疗法,但由于手术风险较低和并发症较少,正逐渐显示出相当大的益处。它也被认为是儿科患者的一种有前景的选择。在这篇综述中,作者讨论了胰岛细胞移植的适应症、手术过程、益处以及改善治疗效果的新策略。