Iwata K
Contrib Microbiol Immunol. 1977;4:77-85.
From studies on high-and-low molecular-weight candidial toxins, with special reference to the etiopathology of experimental-weight candidial toxins, with special reference to the etiopathology of experimental C. albicans infection, it may be concluded that these toxins, particularly the high-molecular-weight ones, play a very important role as parasitic factors in the extablishment of the infection, possibly also affecting its course. This concept of the role of Candidial toxins may be considered also applicable to the establishment of natural candidosis. It is speculated that these toxins might be more or less ubiquitously produced in pathogenic fungi, not only C. albicans but also other species of the genus Candida as well as those of other fungal genera. They may be to some extent related to the etiopathology of their respective fungal infections.
通过对高分子量和低分子量念珠菌毒素的研究,特别是关于实验性白色念珠菌感染的病因病理学,可能得出这样的结论:这些毒素,尤其是高分子量的毒素,作为寄生因素在感染的发生过程中起着非常重要的作用,可能也会影响感染的进程。念珠菌毒素作用的这一概念也可被认为适用于自然念珠菌病的发生。据推测,这些毒素可能或多或少在致病真菌中普遍产生,不仅白色念珠菌,还有念珠菌属的其他物种以及其他真菌属的物种。它们可能在一定程度上与各自真菌感染的病因病理学有关。