Ardita Nadya Fianny, Mithasari Lenny, Untoro Daris, Salasia Siti Isrina Oktavia
Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Department of Clinical Pathology, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Vet World. 2021 May;14(5):1116-1123. doi: 10.14202/vetworld.2021.1116-1123. Epub 2021 May 8.
Methicillin-resistant (MRSA), currently a major problem in hospitals worldwide, is one of the most common causes of nosocomial disease through surgical wound infection. MRSA-infected wounds have very low recovery rates and have become more problematic as some antibiotics are not effective against MRSA. Several antimicrobial and anti-inflammatory agents of green algae () in the form of alkaloids, triterpenoids, steroids, saponins, and flavonoids have the potential to accelerate the wound healing process following MRSA wound infection. Various active compounds contained in the extract are thought to have multiple antibacterial and anti-inflammatory properties that can overcome the MRSA antimicrobial resistance and accelerate tissue growth in the wound healing process. This review aims to describe the potential of extract against MRSA-infected wound healing.
耐甲氧西林金黄色葡萄球菌（MRSA）目前是全球医院面临的一个主要问题，是通过手术伤口感染导致医院疾病的最常见原因之一。感染MRSA的伤口愈合率极低，并且由于一些抗生素对MRSA无效，问题变得更加严重。绿藻中的几种以生物碱、三萜类化合物、类固醇、皂苷和黄酮类化合物形式存在的抗菌和抗炎剂，有可能加速MRSA伤口感染后的伤口愈合过程。绿藻提取物中含有的各种活性化合物被认为具有多种抗菌和抗炎特性，可以克服MRSA的抗菌耐药性，并在伤口愈合过程中加速组织生长。本综述旨在描述绿藻提取物对MRSA感染伤口愈合的潜在作用。
