Páramo-Zunzunegui Javier, Ramos-Carrasco Araceli, Alonso-García Marcos, Cuberes-Montserrat Rosa, Rodríguez-Caravaca Gil, Durán-Poveda Manuel
Department of General Surgery and Digestive Diseases, Hospital Universitario de Móstoles, Madrid, Spain.
International Doctoral Program, University Rey Juan Carlos, Madrid, Spain.
J Nutr Metab. 2020 Nov 7;2020:5049194. doi: 10.1155/2020/5049194. eCollection 2020.
Malnutrition and weight loss in cancer patients is a common problem that affects the prognosis of the disease. In the case of CRC, malnutrition rates range between 30 and 60%.
Description of the preoperative nutritional status of patients diagnosed with colorectal neoplasia who will undergo surgery.
A prospective observational study is performed.
Of 234 patients studied, we observed that 139 (59%) had some degree of nutritional risk. Of all of them, 44.9% ( = 47) had 1-2 points according to MUST and 25% ( = 27) had more than 2 points. No differences were found when studying nutritional risk according to the location of the neoplasm. It was observed that 2.15% of the patients were underweight, 51% overweight, and 23% obese. 19.4% of patients lost less than 5 kg in the 3-6 months prior to diagnosis, 20.7% lost between 5 and 10 kg, and 2.1% lost more than 10 kg. In asymptomatic patients, the weight loss was lower than in symptomatic patients, loss <5 kg, 8.2% vs. 22.8%, and loss 5-10 kg, 16.2% vs. 29.3%, with a value of = 0.016. 5% ( = 7) of the patients had hypoalbuminemia record. 16.5% ( = 23) had some degree of prealbumin deficiency and 20.9% ( = 29) of hypoproteinemia. Symptomatic patients had more frequent analytical alterations, 1-2 altered parameters in 48.8% ( = 20) of asymptomatic vs. 61.2% ( = 22) in the symptomatic, = 0.049.
癌症患者的营养不良和体重减轻是一个常见问题,会影响疾病的预后。在结直肠癌(CRC)病例中,营养不良率在30%至60%之间。
描述将接受手术的结直肠肿瘤患者的术前营养状况。
进行一项前瞻性观察研究。
在研究的234例患者中,我们观察到139例(59%)有某种程度的营养风险。在所有这些患者中,根据营养不良通用筛查工具(MUST),44.9%(n = 47)得1 - 2分,25%(n = 27)得分超过2分。根据肿瘤位置研究营养风险时未发现差异。观察到2.15%的患者体重过轻,51%超重,23%肥胖。19.4%的患者在诊断前3 - 6个月体重减轻少于5千克,20.7%的患者体重减轻5至10千克,2.1%的患者体重减轻超过10千克。无症状患者的体重减轻低于有症状患者,体重减轻<5千克,分别为8.2%对22.8%,体重减轻5 - 10千克,分别为16.2%对29.3%,P值 = 0.016。5%(n = 7)的患者有低白蛋白血症记录。16.5%(n = 23)有某种程度的前白蛋白缺乏,20.9%(n = 29)有低蛋白血症。有症状患者的血液分析改变更频繁,无症状患者中48.8%(n = 20)有1 - 2项参数改变,有症状患者中为61.2%(n = 22),P值 = 0.049。