Curran Thomas
Division of Colon and Rectal Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina.
Clin Colon Rectal Surg. 2023 Jan 25;36(3):192-197. doi: 10.1055/s-0043-1761152. eCollection 2023 May.
Malnutrition is common in surgical patients and is associated with substantially increased morbidity and mortality. Dedicated assessment of nutritional status is advised by major nutrition and surgical societies. Assessment may utilize comprehensive and validated nutritional assessment tools or targeted history, physical examination with accompanying serologic markers to identify nutritional risk preoperatively. Emergent surgery in malnourished patients should proceed as the clinical situation dictates with consideration of ostomy or primary anastomosis with proximal fecal diversion to mitigate postoperative infectious complications. Nonemergent surgery should be delayed to facilitate nutritional optimization via oral nutritional supplementation preferably and total parenteral nutrition if necessary for at least 7 to 14 days. Exclusive enteral nutrition may be considered to optimize nutritional status and inflammation in patients with Crohn's disease. Immunonutrition use in the preoperative setting is not supported by evidence. Perioperative and postoperative immunonutrition may be of benefit but requires dedicated study in the contemporary era. Close attention to preoperative nutritional status and optimization represents a critical opportunity to improve outcomes in patients undergoing colorectal surgery.
营养不良在外科手术患者中很常见,且与发病率和死亡率大幅增加相关。主要的营养和外科学会建议对营养状况进行专门评估。评估可采用全面且经过验证的营养评估工具,或针对性的病史、体格检查以及相关的血清学标志物,以在术前识别营养风险。对于营养不良患者的急诊手术,应根据临床情况进行,考虑行造口术或一期吻合并近端粪便转流,以减轻术后感染并发症。非急诊手术应推迟,以便通过口服营养补充剂(如有必要,可联合全肠外营养)优化营养状况至少7至14天。对于克罗恩病患者,可考虑采用全肠内营养来优化营养状况和炎症。术前使用免疫营养尚无证据支持。围手术期和术后使用免疫营养可能有益,但需要当代的专门研究。密切关注术前营养状况并进行优化是改善结直肠手术患者预后的关键契机。