Aliahmadi Mitra, Amiri Fatemehsadat, Bahrami Leila Sadat, Hosseini Agha Fatemeh, Abiri Behnaz, Vafa Mohammadreza
Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
J Diabetes Metab Disord. 2021 Apr 21;20(1):673-682. doi: 10.1007/s40200-021-00798-z. eCollection 2021 Jun.
This study aimed to investigate the effects of raw red beetroot consumption on metabolic markers and cognitive function in type 2 diabetes patients.
In a quasi-experimental study, 44 type 2 diabetes patients (57 ± 4.5 years) consumed raw red beetroot (100 g, daily), for 8 weeks. Metabolic markers including body weight, glucose and lipid profile parameters, inflammatory and oxidative stress markers, paraoxonase-1 activity, hepatic enzymes, blood pressure and cognitive function were measured at the beginning and end of 8 weeks.
Raw red beetroot consumption resulted in a significant decrease in fasting blood sugar (FBS) levels (-13.53 mg/dL), glycosylated hemoglobin (HbA1c)(-0.34%), apolipoproteinB100 (ApoB100) (-8.25 mg/dl), aspartate aminotransferase (AST) (-1.75 U/L), alanine aminotransferase (ALT) (-3.7 U/L), homocysteine (-7.88 μmol/l), systolic (-0.73 mmHg) and diastolic blood pressure (-0.34 mmHg), anda significant increase in total antioxidant capacity (TAC) (105 μmol/L) and cognitive function tests (all values <0.05). Other variables did not change significantly after the intervention.
Raw red beetroot consumption for 8 weeks in T2DM patients has beneficial impacts on cognitive function, glucose metabolism and other metabolic markers.
本研究旨在调查食用生红甜菜根对2型糖尿病患者代谢指标和认知功能的影响。
在一项准实验研究中，44名2型糖尿病患者（57±4.5岁）每天食用100克生红甜菜根，持续8周。在8周开始和结束时测量代谢指标，包括体重、血糖和血脂参数、炎症和氧化应激指标、对氧磷酶-1活性、肝酶、血压和认知功能。
食用生红甜菜根导致空腹血糖（FBS）水平显著降低（-13.53毫克/分升）、糖化血红蛋白（HbA1c）（-0.34%）、载脂蛋白B100（ApoB100）（-8.25毫克/分升）、天冬氨酸转氨酶（AST）（-1.75单位/升）、丙氨酸转氨酶（ALT）（-3.7单位/升）、同型半胱氨酸（-7.88微摩尔/升）、收缩压（-0.73毫米汞柱）和舒张压（-0.34毫米汞柱），总抗氧化能力（TAC）显著增加（105微摩尔/升）以及认知功能测试（所有值<0.05）。干预后其他变量无显著变化。
2型糖尿病患者食用8周生红甜菜根对认知功能、糖代谢和其他代谢指标有有益影响。
