Aryannejad Armin, Eghtesad Sareh, Rahimi Zahra, Mohammadi Zahra, Malihi Reza, Danehchin Leila, Paridar Yousef, Abolnezhadian Farhad, Cheraghian Bahman, Mard Ali, Gholami Bahareh, Zakeri Amir Mohammad, Tabary Mohammadreza, Masoudi Sahar, Naderian Mohammad Reza, Shayesteh Ali Akbar, Poustchi Hossein
School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
J Diabetes Metab Disord. 2021 May 17;20(1):747-756. doi: 10.1007/s40200-021-00811-5. eCollection 2021 Jun.
Metabolic syndrome (MetS) is a cluster of risk factors, mainly central obesity, insulin resistance, and dyslipidemia, leading to life-threatening cardiovascular diseases. The prevalence of MetS can vary based on different ethnicities and many cultural and lifestyle factors.
We aimed to evaluate the prevalence of MetS and possible correlations with lifestyle-associated factors among different ethnicities in Khuzestan, Iran.
This cross-sectional study was conducted in Khuzestan province of Iran, among 30,504 participants aged 20-65 years, between October 2016 and November 2019. Data was collected through questionnaires along with anthropometric and biological measurements. The National Cholesterol Education Program Adult Treatment Panel III definition was used to estimate MetS prevalence.
Overall, 31.9% (95% CI 31.4-32.4) had MetS (34.2% [95% CI 33.3-35.1] among males; 30.7% [95% CI 30.0-31.3] among females [p < 0.001]). Central obesity, elevated fasting blood sugar levels, and dyslipidemia were the most common abnormalities among those with MetS. The risk of MetS was estimated to increase by age, male gender, residing in urban regions, lower educational levels, lower physical activity levels, lower sleep time, and a positive family history of diabetes mellitus (p < 0.001). Individuals of the Arab and Bakhtiary ethnicities had the highest and lowest risk of MetS, respectively.
MetS prevalence varied among different ethnicities. Aging and some lifestyle-associated factors such as physical activity and sleep time were related to the risk of MetS. Raising awareness about risk factors of MetS would be of great value in setting new health policies to manage the rising trend of MetS.
代谢综合征（MetS）是一组危险因素，主要包括中心性肥胖、胰岛素抵抗和血脂异常，可导致危及生命的心血管疾病。MetS的患病率会因不同种族以及许多文化和生活方式因素而有所不同。
我们旨在评估伊朗胡齐斯坦不同种族中MetS的患病率及其与生活方式相关因素的可能关联。
这项横断面研究于2016年10月至2019年11月在伊朗胡齐斯坦省对30504名年龄在20 - 65岁的参与者进行。通过问卷以及人体测量和生物学测量收集数据。采用美国国家胆固醇教育计划成人治疗小组第三次报告的定义来估计MetS的患病率。
总体而言，31.9%（95%置信区间31.4 - 32.4）患有MetS（男性为34.2% [95%置信区间33.3 - 35.1]；女性为30.7% [95%置信区间30.0 - 31.3] [p < 0.001]）。中心性肥胖、空腹血糖水平升高和血脂异常是患有MetS者中最常见的异常情况。据估计，MetS的风险会随着年龄增长、男性性别、居住在城市地区、教育水平较低、身体活动水平较低、睡眠时间较短以及有糖尿病家族史而增加（p < 0.001）。阿拉伯族和巴赫蒂亚里族个体患MetS的风险分别最高和最低。
MetS的患病率在不同种族中有所不同。衰老以及一些与生活方式相关的因素，如身体活动和睡眠时间，与MetS的风险有关。提高对MetS危险因素的认识对于制定新的健康政策以应对MetS的上升趋势具有重要价值。
