Omidi Fatemeh, Hajikhani Bahareh, Kazemi Seyyedeh Neda, Tajbakhsh Ardeshir, Riazi Sajedeh, Mirsaeidi Mehdi, Ansari Ali, Ghanbari Boroujeni Masoud, Khalili Farima, Hadadi Sara, Nasiri Mohammad Javad
Department of Cardiology, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Front Cardiovasc Med. 2021 Jun 17;8:695206. doi: 10.3389/fcvm.2021.695206. eCollection 2021.
Cardiomyopathies (CMPs) due to myocytes involvement are among the leading causes of sudden adolescent death and heart failure. During the COVID-19 pandemic, there are limited data available on cardiac complications in patients with COVID-19, leading to severe outcomes. We conducted a systematic search in Pubmed/Medline, Web of Science, and Embase databases up to August 2020, for all relevant studies about COVID-19 and CMPs. A total of 29 articles with a total number of 1460 patients were included. Hypertension, diabetes, obesity, hyperlipidemia, and ischemic heart disease were the most reported comorbidities among patients with COVID-19 and cardiomyopathy. In the laboratory findings, 21.47% of patients had increased levels of troponin. Raised D-dimer levels were also reported in all of the patients. Echocardiographic results revealed mild, moderate, and severe Left Ventricular (LV) dysfunction present in 17.13, 11.87, and 10% of patients, respectively. Cardiac injury and CMPs were common conditions in patients with COVID-19. Therefore, it is suggested that cardiac damage be considered in managing patients with COVID-19.
由于心肌细胞受累导致的心肌病（CMPs）是青少年猝死和心力衰竭的主要原因之一。在新冠疫情期间，关于新冠患者心脏并发症的数据有限，这导致了严重的后果。我们在截至2020年8月的PubMed/Medline、科学网和Embase数据库中进行了系统检索，以查找所有关于新冠和CMPs的相关研究。共纳入29篇文章，涉及1460名患者。高血压、糖尿病、肥胖、高脂血症和缺血性心脏病是新冠合并心肌病患者中报告最多的合并症。在实验室检查结果中，21.47%的患者肌钙蛋白水平升高。所有患者均报告D-二聚体水平升高。超声心动图结果显示，分别有17.13%、11.87%和10%的患者存在轻度、中度和重度左心室（LV）功能障碍。心脏损伤和CMPs在新冠患者中很常见。因此，建议在管理新冠患者时考虑心脏损伤。
