Hunan Key Laboratory of Processed Food For Special Medical Purpose, Hunan Key Laboratory of Edible Forestry Resources Safety and Processing Utilization, National Engineering Laboratory for Rice and By-product Deep Processing, School of Food Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, China.
Food Funct. 2021 Aug 21;12(16):7108-7125. doi: 10.1039/d1fo01265g. Epub 2021 Jul 5.
Bioactive peptides are a class of peptides with special physiological functions and have potential applications in human health and disease prevention. Bioactive peptides have gained much research attention because they affect the cardiovascular, endocrine, immune, and nervous systems. Recent research has reported that bioactive peptides are of great value for physiological function regulation, including antioxidation, anti-hypertension, antithrombosis, antibacterial properties, anti-cancer, anti-inflammation, anti-diabetic, anti-obesity, cholesterol-lowering, immunoregulation, mineral binding and opioid activities. The production of food-derived bioactive peptides is mainly through the hydrolysis of digestive enzymes and proteolytic enzymes or microbial fermentation. The purpose of this review is to introduce the production, function, application, challenges, and prospects of food-derived bioactive peptides.
生物活性肽是一类具有特殊生理功能的肽,在人类健康和疾病预防方面具有潜在的应用价值。生物活性肽因其影响心血管、内分泌、免疫和神经系统而受到广泛关注。最近的研究表明,生物活性肽在生理功能调节方面具有重要价值,包括抗氧化、降血压、抗血栓形成、抗菌特性、抗癌、抗炎、降血糖、抗肥胖、降胆固醇、免疫调节、矿物质结合和阿片样活性。食物来源的生物活性肽的生产主要通过消化酶和蛋白酶的水解或微生物发酵。本综述的目的是介绍食物来源的生物活性肽的生产、功能、应用、挑战和前景。