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生物活性肽

Bioactive peptides.

作者信息

Shahidi Fereidoon, Zhong Ying

机构信息

Memorial University of Newfoundland, Department of Biochemistry, 300 Prince Philip Dr, St. John's, NL, Canada.

出版信息

J AOAC Int. 2008 Jul-Aug;91(4):914-31.

PMID:18727554
Abstract

Peptides with biological activities, released during gastrointestinal digestion or food processing, play an important role in metabolic regulation and modulation, suggesting their potential use as nutraceuticals and functional food ingredients for health promotion and disease risk reduction. Many studies have reported that peptides from various food sources possess bioactivities, including antihypertensive, antioxidant, anticancer, antimicrobial, and opioid activities as well as immunomodulatory and cholesterol-lowering effects. More studies are being performed exploring the sources, bioavailabilities, and possible physiological/functional properties and the mechanisms of action of bioactive peptides. Technological approaches in terms of peptide preparation, purification, and characterization have also been investigated.

摘要

在胃肠道消化或食品加工过程中释放的具有生物活性的肽,在代谢调节中发挥着重要作用,这表明它们有可能作为营养保健品和功能性食品成分用于促进健康和降低疾病风险。许多研究报告称,来自各种食物来源的肽具有生物活性,包括抗高血压、抗氧化、抗癌、抗菌和阿片样物质活性,以及免疫调节和降胆固醇作用。正在进行更多研究以探索生物活性肽的来源、生物利用度、可能的生理/功能特性以及作用机制。在肽的制备、纯化和表征方面的技术方法也已得到研究。

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