Kamal Natasha, Motwani Kiran, Wellington Jennifer, Wong Uni, Cross Raymond K
University of Maryland School of Medicine, Baltimore, Maryland, USA.
Crohns Colitis 360. 2021 Feb 24;3(2):otab013. doi: 10.1093/crocol/otab013. eCollection 2021 Apr.
Fecal incontinence (FI) is frequently reported in inflammatory bowel disease (IBD).
We retrospectively reviewed data from the Study of a Prospective Adult Research Cohort with IBD registry.
Three hundred forty-seven patients had Crohn disease and 145 had ulcerative colitis. 14.2% of patients reported FI. FI was associated with active disease. FI was not associated with disease location, phenotype, or perianal involvement. Greater than 50 years of age or 15 years of disease increased the odds of FI and remission decreased the odds of FI.
Further research into the mechanism of FI in IBD is needed.
炎症性肠病（IBD）患者中经常有大便失禁（FI）的报告。
我们回顾性分析了来自IBD前瞻性成人研究队列注册库的数据。
347例患者患有克罗恩病，145例患有溃疡性结肠炎。14.2%的患者报告有大便失禁。大便失禁与疾病活动相关。大便失禁与疾病部位、表型或肛周受累无关。年龄大于50岁或病程超过15年会增加大便失禁的几率，而病情缓解则会降低大便失禁的几率。
需要对IBD中大便失禁的机制进行进一步研究。
