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轻度创伤性颅内出血:识别预后因素并比较预后良好和不良的患者。

Minor Traumatic Intracranial Hemorrhage: Identifying Prognostic Factors and Comparing Patients with Favorable and Unfavorable Outcomes.

机构信息

Emergency Department, Chi-Mei Medical Center, Tainan, Taiwan.

Division of Traumatology, Department of Surgery, Chi-Mei Medical Center, Tainan, Taiwan.

出版信息

World Neurosurg. 2021 Sep;153:e428-e434. doi: 10.1016/j.wneu.2021.06.137. Epub 2021 Jul 3.

DOI:10.1016/j.wneu.2021.06.137
PMID:34229100
Abstract

BACKGROUND

Whether patients with minor traumatic intracranial hemorrhage (MTICH) require intensive care remains uncertain. This study aimed to identify the factors affecting the postinjury neurologic outcomes of patients with MTICH to determine optimal care.

METHODS

We retrospectively reviewed the data of all patients with trauma discharged from a tertiary trauma center during a 2-year period and included adult patients with isolated MTICH. Patient Glasgow Outcome Scale (GOS) score at discharge was the primary outcome measurement. A GOS score of 4 or 5 was defined as a favorable outcome, and a score of 1-3 was considered an unfavorable outcome. We compared the clinical data between favorable and unfavorable outcome groups to determine the differences between groups.

RESULTS

Of the 11,814 patients considered, we identified 534 patients who met the inclusion criteria. Older adults accounted for 35.4% of the study cohort. Only 4 complications (0.7%) and 1 mortality (0.2%) were observed during hospitalization. The number of patients who requiring brain surgery, transfusion, mechanical ventilation, pressor, or invasive monitor was 5 (0.9%), 5 (0.9%), 3 (5.6%), 0 (0%), and 0 (0%), respectively. After multivariate analysis, we discovered that comorbidities, brain surgery requirement, respiratory rate, and Trauma Injury Severity Score were strongly associated with patient GOS score at discharge.

CONCLUSIONS

MTICH rarely resulted in permanent morbidity and mortality. Older patients exhibited higher incidences of MTICH and were at a higher risk for unfavorable outcomes.

摘要

背景

轻度创伤性颅内出血(MTICH)患者是否需要重症监护仍不确定。本研究旨在确定影响 MTICH 患者损伤后神经预后的因素,以确定最佳治疗方案。

方法

我们回顾性分析了 2 年内一家三级创伤中心出院的所有创伤患者的数据,并纳入了单纯 MTICH 的成年患者。出院时患者的格拉斯哥预后量表(GOS)评分是主要的预后测量指标。GOS 评分为 4 或 5 定义为良好预后,评分为 1-3 定义为不良预后。我们比较了良好和不良预后组之间的临床数据,以确定组间差异。

结果

在考虑的 11814 名患者中,我们确定了 534 名符合纳入标准的患者。研究队列中老年人占 35.4%。住院期间仅观察到 4 例并发症(0.7%)和 1 例死亡(0.2%)。需要进行脑部手术、输血、机械通气、升压或有创监测的患者人数分别为 5(0.9%)、5(0.9%)、3(5.6%)、0(0%)和 0(0%)。多变量分析后,我们发现合并症、脑部手术需求、呼吸频率和创伤损伤严重程度评分与患者出院时的 GOS 评分密切相关。

结论

MTICH 很少导致永久性发病率和死亡率。老年患者 MTICH 的发生率更高,不良预后的风险更高。

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