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基于反向传播神经网络和扩展集成员滤波器的自动脑肿瘤诊断方法。

Automatic brain tumour diagnostic method based on a back propagation neural network and an extended set-membership filter.

机构信息

State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China; Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang 110169, China.

State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China; Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang 110169, China; University of Chinese Academy of Sciences, Beijing 100049, China.

出版信息

Comput Methods Programs Biomed. 2021 Sep;208:106188. doi: 10.1016/j.cmpb.2021.106188. Epub 2021 Jun 2.

Abstract

BACKGROUND

Diagnosing brain tumours remains a challenging task in clinical practice. Despite their questionable accuracy, magnetic resonance image (MRI) scans are presently considered the optimal facility for assessing the growth of tumours. However, the efficiency of manual diagnosis is low, and high computational cost and poor convergence restrict the application of machine learning methods. This study aims to design a method that can reliably diagnose brain tumours from MRI scans.

METHODS

First, image pre-processing (which includes background removal, size standardization, noise removal, and contrast enhancement) is utilized to normalize the images. Then, grey level co-occurrence matrix features are selected as texture features of the brain MRI scans. Finally, a method combining a back propagation neural network (BPNN) and an extended set-membership filter (ESMF) is proposed to classify features and perform image classification.

RESULTS

A total of 304 patient MRI series (247 images of brains with tumours and 57 images of normal brains) were included and assessed in this study. The results revealed that our proposed method can achieve an accuracy of 95.40% and has classification accuracies of 97.14% and 88.24% for brain tumour and normal brain, respectively.

CONCLUSION

This study proposes an automatic brain tumour detection model constructed using a combination of BPNN and ESMF. The model is found to be able to accurately classify brain MRI scans as normal or tumour images.

摘要

背景

在临床实践中,诊断脑肿瘤仍然是一项具有挑战性的任务。尽管磁共振成像(MRI)扫描的准确性存在争议,但目前仍被认为是评估肿瘤生长的最佳方法。然而,手动诊断的效率较低,计算成本高和收敛性差限制了机器学习方法的应用。本研究旨在设计一种能够可靠地从 MRI 扫描中诊断脑肿瘤的方法。

方法

首先,进行图像预处理(包括背景去除、尺寸标准化、噪声去除和对比度增强),以归一化图像。然后,选择灰度共生矩阵特征作为脑 MRI 扫描的纹理特征。最后,提出了一种结合反向传播神经网络(BPNN)和扩展集成员滤波器(ESMF)的方法来对特征进行分类和图像分类。

结果

本研究共纳入和评估了 304 例患者的 MRI 系列(247 例脑肿瘤图像和 57 例正常脑图像)。结果表明,我们提出的方法可以达到 95.40%的准确率,对脑肿瘤和正常脑的分类准确率分别为 97.14%和 88.24%。

结论

本研究提出了一种基于 BPNN 和 ESMF 组合的自动脑肿瘤检测模型。该模型能够准确地将脑 MRI 扫描分类为正常或肿瘤图像。

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