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瑞典全国范围内 1910 至 1978 年流感和自杀死亡的时间序列分析。

Swedish nationwide time series analysis of influenza and suicide deaths from 1910 to 1978.

机构信息

Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden

Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.

出版信息

BMJ Open. 2021 Jul 7;11(7):e049302. doi: 10.1136/bmjopen-2021-049302.

Abstract

OBJECTIVES

There is concern that the COVID-19 pandemic will be associated with an increase in suicides, but evidence supporting a link between pandemics and suicide is limited. Using data from the three influenza pandemics of the 20th century, we aimed to investigate whether an association exists between influenza deaths and suicide deaths.

DESIGN

Time series analysis.

SETTING

Sweden.

PARTICIPANTS

Deaths from influenza and suicides extracted from the Statistical Yearbook of Sweden for 1910-1978, covering three pandemics (the Spanish influenza, the Asian influenza and the Hong Kong influenza).

MAIN OUTCOME MEASURES

Annual suicide rates in Sweden among the whole population, men and women. Non-linear autoregressive distributed lag models was implemented to explore if there is a short-term and/or long-term relationship of increases and decreases in influenza death rates with suicide rates during 1910-1978.

RESULTS

Between 1910 and 1978, there was no evidence of either short-term or long-term significant associations between influenza death rates and changes in suicides (β coefficients of 0.00002, p=0.931 and β=0.00103, p=0.764 for short-term relationship of increases and decreases in influenza death rates, respectively, with suicide rates, and β=-0.0002, p=0.998 and β=0.00211, p=0.962 for long-term relationship of increases and decreases in influenza death rates, respectively, with suicide rates). The same pattern emerged in separate analyses for men and women.

CONCLUSIONS

We found no evidence of short-term or long-term association between influenza death rates and suicide death rates across three 20th century pandemics.

摘要

目的

人们担心 COVID-19 大流行会导致自杀人数增加,但支持大流行与自杀之间存在关联的证据有限。我们利用 20 世纪三次流感大流行的数据,旨在调查流感死亡与自杀死亡之间是否存在关联。

设计

时间序列分析。

地点

瑞典。

参与者

从 1910 年至 1978 年的瑞典统计年鉴中提取的流感和自杀死亡人数,涵盖了三次大流行(西班牙流感、亚洲流感和香港流感)。

主要观察指标

瑞典全人群、男性和女性的年自杀率。采用非线性自回归分布滞后模型来探讨 1910 年至 1978 年期间,流感死亡率的增加和减少与自杀率之间是否存在短期和/或长期关系。

结果

在 1910 年至 1978 年期间,流感死亡率与自杀率的变化之间没有短期或长期的显著关联(流感死亡率增加和减少的短期关系的β系数分别为 0.00002,p=0.931 和β=0.00103,p=0.764,与自杀率的关系,以及流感死亡率增加和减少的长期关系的β系数分别为-0.0002,p=0.998 和β=0.00211,p=0.962,与自杀率的关系)。在针对男性和女性的单独分析中也出现了相同的模式。

结论

我们没有发现 20 世纪三次大流行期间流感死亡率与自杀死亡率之间存在短期或长期关联的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c5/8266430/22f5fada1575/bmjopen-2021-049302f01.jpg

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