食蟹猴在神经生物学中的应用现状及展望。

Current Status of and Perspectives on the Application of Marmosets in Neurobiology.

机构信息

Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan; email:

Laboratory for Marmoset Neural Architecture, RIKEN Center for Brain Science, Wako-shi, Saitama 351-0198, Japan.

出版信息

Annu Rev Neurosci. 2021 Jul 8;44:27-48. doi: 10.1146/annurev-neuro-030520-101844. Epub 2020 Dec 2.

DOI:10.1146/annurev-neuro-030520-101844

PMID:34236888

Abstract

The common marmoset (), a small New World primate, is receiving substantial attention in the neuroscience and biomedical science fields because its anatomical features, functional and behavioral characteristics, and reproductive features and its amenability to available genetic modification technologies make it an attractive experimental subject. In this review, I outline the progress of marmoset neuroscience research and summarize both the current status (opportunities and limitations) of and the future perspectives on the application of marmosets in neuroscience and disease modeling.

摘要

普通狨猴（），一种小型新世界灵长类动物，在神经科学和生物医学科学领域受到广泛关注，因为其解剖学特征、功能和行为特征、生殖特征以及对现有遗传修饰技术的适应性使它成为一个有吸引力的实验对象。在这篇综述中，我概述了狨猴神经科学研究的进展，并总结了狨猴在神经科学和疾病建模中的应用的现状（机遇和局限性）和未来展望。