Lin Yan, Song Yu, Xu Ying, Yao Ru, Zhou Xing-Tong, Wang Chang-Jun, Huang Xin, Wang Xue-Fei, Cao Xi, Sun Qiang
Department of Breast Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2021 Jun 30;43(3):395-401. doi: 10.3881/j.issn.1000-503X.13752.
Objective To evaluate the application value of abbreviated comprehensive geriatric assessment(aCGA)in elderly female breast cancer patients. Methods Eight aspects of the traditional CGA were simplified to form the aCGA assessment table,based on which the patients were classified into three grades of A,B and C according to the total scores.This study enrolled the elderly female patients with breast cancer aged 70 years and above who were treated in PUMC Hospital from June 2018 to January 2020.Eastern Cooperative Oncology Group(ECOG)scoring and aCGA grading were performed respectively,and the results of the two methods were compared. Results Of the 162 patients,111(68.5%)were classified by the aGGA method as grade A,43(26.5%)as grade B,and 8(5.0%)as grade C;131(80.9%)cases have concurrent diseases,and the most common complications were hypertension(=89),cardiovascular diseases(=47)and diabetes mellitus(=39).The ECOG score was 0-1 in 133(82.0%)cases,2 in 24(14.8%)cases and 3 in 5(3.2%)cases.The ECOG score showed 133(82.0%)cases with good status and 29 cases with poor status.However,according to the aCGA classification,111 cases were in good health status and 51 cases were in poor health status;the difference in the result between the two groups was statistically significant( =14.24,<0.001).Conclusion Compared with ECOG score,aCGA grading can more comprehensively evaluate the health status of elderly female breast cancer patients and can be applied to the patients aged 70 and above.
目的 评估简化综合老年评估(aCGA)在老年女性乳腺癌患者中的应用价值。方法 将传统综合老年评估的八个方面进行简化,形成aCGA评估表,并根据总分将患者分为A、B、C三个等级。本研究纳入2018年6月至2020年1月在我院治疗的70岁及以上老年女性乳腺癌患者,分别进行东部肿瘤协作组(ECOG)评分和aCGA分级,并比较两种方法的结果。结果 162例患者中,aGGA法分级为A级111例(68.5%),B级43例(26.5%),C级8例(5.0%);131例(80.9%)有合并症,最常见的合并症为高血压(89例)、心血管疾病(47例)和糖尿病(39例)。ECOG评分0~1分者133例(82.0%),2分者24例(14.8%),3分者5例(3.2%)。ECOG评分显示133例(82.0%)状态良好,29例状态较差。而根据aCGA分级,健康状态良好者111例,较差者51例;两组结果差异有统计学意义( =14.24,<0.001)。结论 与ECOG评分相比,aCGA分级能更全面地评估老年女性乳腺癌患者的健康状态,可应用于70岁及以上患者。