Celik Mehmet, Yilmaz Yusuf, Karagoz Ali, Kahyaoglu Muzaffer, Cakmak Ender Ozgun, Kup Ayhan, Celik Fatma Betül, Karaduman Ahmet, Kulahcioglu Seyhmus, Izci Servet, Gecmen Cetin, Caliskan Mustafa
Kartal Kosuyolu Education and Research Hospital, Department of Cardiology, Istanbul, Turkey.
Istanbul Medeniyet University, Department of Cardiology, Istanbul, Turkey.
Medeni Med J. 2021;36(2):83-90. doi: 10.5222/MMJ.2021.08364. Epub 2021 Jun 18.
The new coronavirus disease (COVID-19) has spread rapidly all over the world and caused anxiety disorders. Recent studies have also shown that the prevalence of depression and anxiety increased during the COVID-19 outbreak. We aimed to evaluate the anxiety and depression levels during the pandemic and identify the effect of pandemic-related stress on blood pressure (BP) control in primary hypertensive patients.
A total of 142 patients with primary hypertension (HT) who continued to use the same antihypertensive drugs before and during the pandemic were included in the study. Twenty-four -hour Ambulatory Blood Pressure Monitoring (ABPM) and the Hospital Anxiety and Depression Scale (HADS) questionnaire were applied to patients. We retrospectively reviewed 24-h ABPM records of the same patients for the year before the pandemic.
Daytime, nighttime and 24 -hour-systolic blood pressure (SBP) levels as well as daytime, nighttime, and 24- hour-diastolic blood pressure (DBP) levels , were significantly elevated during the COVID-19 outbreak compared to the pre-pandemic period (p<0.001). Higher HADS-A scores (HADS-A ≥7) were significantly associated with much greater increase in BP compared to the patients with lower HADS-A scores.
Psychological stress due to the COVID-19 outbreak led to worsening of the regulation of BP in controlled hypertensive patients whose antihypertensive treatments did not change.
新型冠状病毒病（COVID-19）已在全球迅速传播并引发焦虑症。近期研究还表明，在COVID-19疫情期间，抑郁和焦虑的患病率有所上升。我们旨在评估疫情期间的焦虑和抑郁水平，并确定疫情相关压力对原发性高血压患者血压（BP）控制的影响。
本研究纳入了142例原发性高血压（HT）患者，这些患者在疫情前和疫情期间持续使用相同的降压药物。对患者进行了24小时动态血压监测（ABPM）和医院焦虑抑郁量表（HADS）问卷调查。我们回顾性分析了这些患者在疫情前一年的24小时ABPM记录。
与疫情前相比，COVID-19疫情期间白天、夜间和24小时收缩压（SBP）水平以及白天、夜间和24小时舒张压（DBP）水平均显著升高（p<0.001）。与HADS-A得分较低的患者相比，HADS-A得分较高（HADS-A≥7）的患者血压升高幅度明显更大。
COVID-19疫情引发的心理压力导致接受不变降压治疗的高血压控制患者的血压调节恶化。
