Respiratory Sciences, University of Leicester, Leicester, UK.
School of Law, The University of Edinburgh, Edinburgh, UK.
BMJ Open. 2021 Jul 9;11(7):e049611. doi: 10.1136/bmjopen-2021-049611.
As the world continues to grapple with the COVID-19 pandemic, emerging evidence suggests that individuals from ethnic minority backgrounds may be disproportionately affected. The United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers (UK-REACH) project has been initiated to generate rapid evidence on whether and why ethnicity affects COVID-19 diagnosis and clinical outcomes in healthcare workers (HCWs) in the UK, through five interlinked work packages/work streams, three of which form the basis of this protocol. The ethico-legal work (Work Package 3) aims to understand and address legal, ethical and acceptability issues around big data research; the HCWs' experiences study (Work Package 4) explores their work and personal experiences, perceptions of risk, support and coping mechanisms; the stakeholder engagement work (Work Package 5) aims to provide feedback and support with the formulation and dissemination of the project recommendations.
Work Package 3 has two different research strands: (A) desk-based doctrinal research; and (B) empirical qualitative research with key opinion leaders. For the empirical research, in-depth interviews will be conducted digitally and recorded with participants' permission. Recordings will be transcribed, coded and analysed using thematic analysis. In Work Package 4, online in-depth interviews and focus groups will be conducted with approximately 150 HCWs, from across the UK, and these will be recorded with participants' consent. The recordings will be transcribed and coded and data will be analysed using thematic analysis. Work Package 5 will achieve its objectives through regular group meetings and in-group discussions.
Ethical approval has been received from the London-Brighton & Sussex Research Ethics Committee of the Health Research Authority (Ref No 20/HRA/4718). Results of the study will be published in open-access journals, and disseminated through conference presentations, project website, stakeholder organisations, media and scientific advisory groups.
ISRCTN11811602.
随着世界继续应对 COVID-19 大流行，新出现的证据表明，少数民族背景的人可能受到不成比例的影响。英国研究项目“种族与医疗保健工作者 COVID-19 结果研究（UK-REACH）”旨在通过五个相互关联的工作包/工作流快速生成证据，以了解和解释为什么种族会影响英国医疗保健工作者（HCWs）的 COVID-19 诊断和临床结果，其中三个构成了本方案的基础。伦理法律工作（工作包 3）旨在了解和解决大数据研究中的法律、伦理和可接受性问题；HCWs 的经验研究（工作包 4）探讨了他们的工作和个人经验、风险感知、支持和应对机制；利益相关者参与工作（工作包 5）旨在为项目建议的制定和传播提供反馈和支持。
工作包 3 有两个不同的研究方向：（A）基于文献的理论研究；和（B）与主要意见领袖进行的实证定性研究。对于实证研究，将在参与者同意的情况下，通过数字方式进行深入访谈并记录。记录将经过转录、编码和主题分析进行分析。在工作包 4 中，将与来自英国各地的大约 150 名 HCWs 进行在线深入访谈和焦点小组访谈，并在参与者同意的情况下进行记录。录制内容将被转录和编码，使用主题分析对数据进行分析。工作包 5 将通过定期小组会议和小组内讨论来实现其目标。
伦敦-布莱顿和苏塞克斯研究伦理委员会已从健康研究管理局获得伦理批准（参考号 20/HRA/4718）。该研究的结果将发表在开放获取期刊上，并通过会议演讲、项目网站、利益相关者组织、媒体和科学咨询小组进行传播。
ISRCTN87071724。
