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粪便严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）RNA 与降低的 2019 年冠状病毒病（COVID-19）存活率相关。

Fecal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) RNA Is Associated With Decreased Coronavirus Disease 2019 (COVID-19) Survival.

机构信息

Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts, USA.

Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Clin Infect Dis. 2022 Mar 23;74(6):1081-1084. doi: 10.1093/cid/ciab623.

DOI:10.1093/cid/ciab623
PMID:34245255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8406863/
Abstract

The clinical significance of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) RNA in stool remains uncertain. We found that extrapulmonary dissemination of infection to the gastrointestinal tract, assessed by the presence of SARS-CoV-2 RNA in stool, is associated with decreased coronavirus disease 2019 (COVID-19) survival. Measurement of SARS-CoV-2 RNA in stool may have utility for clinical risk assessment.

摘要

严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）在粪便中的临床意义尚不确定。我们发现，通过粪便中存在 SARS-CoV-2 RNA 评估，感染向胃肠道的肺外播散与 2019 冠状病毒病（COVID-19）死亡率降低相关。粪便中 SARS-CoV-2 RNA 的测量可能对临床风险评估有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1ed/8946677/419456689dab/ciab623f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1ed/8946677/419456689dab/ciab623f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1ed/8946677/419456689dab/ciab623f0001.jpg

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