[荷瘤大鼠肝脏中外源化学物的代谢特征]
[Metabolic characteristics of xenobiotics in the liver of tumor-bearing rats].
作者信息
Komov V P, Firsova V I, Vennikas O R
出版信息
Vopr Onkol. 1987;33(12):67-71.
PMID:3424709
Abstract
A study of the condition and function of a multienzymatic monoxygenase system in liver microsomes of rats bearing experimental Pliss' lymphosarcoma and Zajdela's ascites hepatoma showed synthesis and function of the key enzymes of the hydroxylating microsomes of the liver being inhibited and, consequently, drug metabolism slowed down.
摘要
一项关于患有实验性普利斯氏淋巴肉瘤和扎伊德氏腹水肝癌大鼠肝脏微粒体中多酶单加氧酶系统的状况和功能的研究表明，肝脏羟化微粒体关键酶的合成及功能受到抑制，因此药物代谢减缓。
Zotero 插件