Suppr超能文献

一名年轻男性的原发性腹膜后畸胎瘤:病例报告

Primary Retroperitoneal Teratoma in a Young Male: A Case Report.

作者信息

Singh Charan, Raypattanaik Niladri M, Sharma Ishan, Kaman Lileswar

机构信息

General Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, IND.

出版信息

Cureus. 2021 Jun 1;13(6):e15376. doi: 10.7759/cureus.15376. eCollection 2021 Jun.

Abstract

Primary retroperitoneal teratomas are rare non-seminomatous germ cell tumors that arise from embryonal tissues. They form only 5%-10% of all retroperitoneal tumors. These are usually asymptomatic or present as lump or mass with compressive symptoms. Most of the patients are diagnosed by characteristic computed tomography findings. The chances of malignant transformation are rare. Complete surgical resection is the definitive treatment for most patients. We had a 19 years old young man, presented with pain abdomen and awareness of a lump in the right upper abdomen. Contrast-enhanced computed tomography (CECT) of the abdomen revealed a heterogeneous soft tissue mass in the retroperitoneum with calcification. He was successfully treated with en-bloc complete surgical resection. Histopathology confirmed benign mature teratoma including all three germ layers. The patient is doing fine at nine months of follow-up and planned for CECT abdomen. Primary mature teratomas arise in the retroperitoneum due to failure of germ cells migration to their normal location. Germ cells undergo differentiation into various germ layers. Teratomas can be classified as mature, immature, or non-dermal based on their histopathological characteristics. Although complete surgical excision is the mainstay of treatment, malignant teratomas frequently recur. So, annual follow-up is recommended with imaging. A classic mature teratoma requires careful examination and interpretation of the imaging. The amount of immature components determines outcome and recurrence in these patients so en-bloc surgical resection is the treatment of choice.

摘要

原发性腹膜后畸胎瘤是一种罕见的非精原细胞性生殖细胞肿瘤,起源于胚胎组织。它们仅占所有腹膜后肿瘤的5%-10%。这些肿瘤通常无症状,或表现为肿块并伴有压迫症状。大多数患者通过特征性的计算机断层扫描结果得以诊断。恶性转化的几率很低。对于大多数患者而言,完整的手术切除是决定性的治疗方法。我们有一名19岁的年轻男性,因腹痛和右上腹肿块感前来就诊。腹部增强计算机断层扫描(CECT)显示腹膜后有一个不均匀的软组织肿块并伴有钙化。他通过整块完整手术切除获得了成功治疗。组织病理学证实为良性成熟畸胎瘤,包含所有三个胚层。患者在随访9个月时情况良好,并计划进行腹部CECT检查。原发性成熟畸胎瘤发生于腹膜后是由于生殖细胞未能迁移至其正常位置。生殖细胞分化形成各种胚层。畸胎瘤可根据其组织病理学特征分为成熟型、未成熟型或非皮样型。尽管完整手术切除是主要的治疗方法,但恶性畸胎瘤经常复发。因此,建议每年进行影像学随访。典型的成熟畸胎瘤需要对影像学进行仔细检查和解读。未成熟成分的数量决定了这些患者的预后和复发情况,所以整块手术切除是首选的治疗方法。

相似文献

1
Primary Retroperitoneal Teratoma in a Young Male: A Case Report.
Cureus. 2021 Jun 1;13(6):e15376. doi: 10.7759/cureus.15376. eCollection 2021 Jun.
3
Primary retroperitoneal mature teratoma in a young female: Case report.
Int J Surg Case Rep. 2024 Feb;115:109321. doi: 10.1016/j.ijscr.2024.109321. Epub 2024 Jan 28.
4
Primary Mature Teratoma of the Rectum: A Case Report.
Am J Case Rep. 2021 Feb 1;22:e930272. doi: 10.12659/AJCR.930272.
5
Massive primary retroperitoneal immature teratoma in an adult: A case report.
Int J Surg Case Rep. 2021 Apr;81:105775. doi: 10.1016/j.ijscr.2021.105775. Epub 2021 Mar 16.
6
Adult Retroperitoneal Mature Cystic Teratoma Masquerading as Non-Endocrine Primary Adrenal Tumor.
J Coll Physicians Surg Pak. 2021 Nov;31(11):1351-1353. doi: 10.29271/jcpsp.2021.11.1351.
8
Primary teratoma of the adrenal gland: a case report.
Transl Cancer Res. 2022 Aug;11(8):2985-2989. doi: 10.21037/tcr-21-2913.
10
Primary carcinoid tumor arising in a retroperitoneal mature teratoma in an adult.
Int J Urol. 2004 Oct;11(10):912-5. doi: 10.1111/j.1442-2042.2004.00918.x.

引用本文的文献

2
Primary retroperitoneal mature teratoma in a young female: Case report.
Int J Surg Case Rep. 2024 Feb;115:109321. doi: 10.1016/j.ijscr.2024.109321. Epub 2024 Jan 28.

本文引用的文献

1
Retroperitoneal mature cystic teratoma involving the left adrenal gland in a 75-year-old male: a case report and literature review.
J Surg Case Rep. 2020 Nov 24;2020(11):rjaa451. doi: 10.1093/jscr/rjaa451. eCollection 2020 Nov.
2
Mature cystic teratoma presenting as suprarenal mass.
BMJ Case Rep. 2020 Aug 25;13(8):e237734. doi: 10.1136/bcr-2020-237734.
3
Recurrence of retroperitoneal mature cystic teratoma in an adult: A case report.
Radiol Case Rep. 2019 Mar 27;14(6):692-696. doi: 10.1016/j.radcr.2019.03.008. eCollection 2019 Jun.
4
Primary retroperitoneal mature cystic teratoma (dermoid cyst) in a 51-year-old male:Case report and historical literature review.
SAGE Open Med Case Rep. 2017 Mar 23;5:2050313X17700745. doi: 10.1177/2050313X17700745. eCollection 2017.
5
Primary retroperitoneal mature cystic teratoma in an adult: A case report.
Int J Surg Case Rep. 2016;28:285-288. doi: 10.1016/j.ijscr.2016.10.011. Epub 2016 Oct 11.
6
Giant mature primary retroperitoneal teratoma in a young adult: report of a rare case and literature review.
Case Rep Surg. 2014;2014:930538. doi: 10.1155/2014/930538. Epub 2014 Nov 19.
8
Giant primary retroperitoneal teratoma in an adult: a case report.
Case Rep Med. 2010;2010. doi: 10.1155/2010/650424. Epub 2010 Aug 24.
9
Primary retroperitoneal mature cystic teratoma presenting as an adrenal tumor in an adult.
Int J Urol. 2010 Sep;17(9):817. doi: 10.1111/j.1442-2042.2010.02591.x. Epub 2010 Jul 15.
10
Primary retroperitoneal teratomas: a review of the literature.
J Surg Oncol. 2004 May 1;86(2):107-13. doi: 10.1002/jso.20043.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验