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青年女性原发性腹膜后成熟畸胎瘤:病例报告

Primary retroperitoneal mature teratoma in a young female: Case report.

作者信息

Mohammed Sadam Aliye, Kazali Bedri Ahmed, Ibrahim Burhan Mohammed, Mohammed Hidaya Yahya, Gebrechristos Selam, Mersha Mahlet Kifle

机构信息

Department of Surgery, Urology Unit, School of Medicine, Po Box: 9086, Addis Ababa University, Ethiopia.

Department of Surgery, Urology Unit, School of Medicine, Po Box: 9086, Addis Ababa University, Ethiopia.

出版信息

Int J Surg Case Rep. 2024 Feb;115:109321. doi: 10.1016/j.ijscr.2024.109321. Epub 2024 Jan 28.

DOI:10.1016/j.ijscr.2024.109321
PMID:38306872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10850739/
Abstract

INTRODUCTION AND IMPORTANCE

Teratomas are nonseminomatous germ cell tumor. Retroperitoneal teratoma is uncommon, especially in adults. Surgical excision the main stay of therapy for mature teratoma and also it the way for defnitive diagnosis.

CASE PRESENTATION

This case report discuss a 20 year old female patient who presented with long standing abdominal pain. On abdominal examination there was firm, immobile huge mass irregular mass involving left lower and upper abdomen crossing the midline. The ultrasound and CT scan was suggestive of retroperitoneal teratoma. Preoperative CA19.9 was elevated, which drop significantly postoperatively. Patient was explored and complete tumor resection is done. The biopsy confirms mature teratoma. The postoperative follow up was unremarkable.

CLINICAL DISCUSSION

Retroperitoneal teratomas are very rare in adults and only few cases have been reported in literature. Primary retroperitoneal teratomas (PRT) are rare, with incidence of 1 %-11 %. Imaging has vital role for diagnosis of retroperitoneal. Tumor markers can be elevated in PRT. Most mature teratomas are benign in nature. Surgical excision is necessary for definitive diagnosis and it is main stay of management for retroperitoneal teratoma.

CONCLUSION

Preoperative Imaging is important not only for diagnosis but also for preoperative planning. Surgical resection is the main stay of management for mature retroperitoneal teratoma. Despite its benign nature mature retroperitoneal teratoma need close follow up, because of its low risk of malignant transformation.

摘要

引言与重要性

畸胎瘤是非精原性生殖细胞肿瘤。腹膜后畸胎瘤并不常见,尤其是在成年人中。手术切除是成熟畸胎瘤治疗的主要手段,也是明确诊断的方法。

病例介绍

本病例报告讨论了一名20岁女性患者,她长期存在腹痛。腹部检查发现有一个坚硬、固定的巨大肿块,为不规则肿块,累及左下腹和上腹部并跨越中线。超声和CT扫描提示为腹膜后畸胎瘤。术前CA19.9升高,术后显著下降。对患者进行了探查并完成了肿瘤切除。活检证实为成熟畸胎瘤。术后随访无异常。

临床讨论

腹膜后畸胎瘤在成年人中非常罕见,文献中仅报道了少数病例。原发性腹膜后畸胎瘤(PRT)罕见,发病率为1%-11%。影像学对腹膜后肿瘤的诊断起着至关重要的作用。PRT中肿瘤标志物可能升高。大多数成熟畸胎瘤本质上是良性的。手术切除对于明确诊断是必要的,也是腹膜后畸胎瘤治疗的主要手段。

结论

术前影像学不仅对诊断很重要,而且对术前规划也很重要。手术切除是成熟腹膜后畸胎瘤治疗的主要手段。尽管成熟腹膜后畸胎瘤本质上是良性的,但由于其恶性转化风险低,仍需要密切随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95f6/10850739/e9dd5636e954/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95f6/10850739/e3175adbcc43/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95f6/10850739/b8f644820560/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95f6/10850739/6c82285c7e6c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95f6/10850739/e9dd5636e954/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95f6/10850739/e3175adbcc43/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95f6/10850739/b8f644820560/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95f6/10850739/6c82285c7e6c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95f6/10850739/e9dd5636e954/gr4.jpg

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