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50 岁及以上患者中近期诊断疾病与 COVID-19 住院之间的关联分析——基于 SHARE 的研究。

Associations Between Recently Diagnosed Conditions and Hospitalization due to COVID-19 in Patients Aged 50 Years and Older-A SHARE-Based Analysis.

机构信息

Department of Physical Medicine and Nursing, University of Zaragoza, Spain.

National Research Centre for the Working Environment, Copenhagen, Denmark.

出版信息

J Gerontol A Biol Sci Med Sci. 2022 Apr 1;77(4):e111-e114. doi: 10.1093/gerona/glab199.

Abstract

BACKGROUND

Only a few studies have been carried out with a large sample size on the relationship between chronic conditions and hospitalization for coronavirus disease 2019 (COVID-19), and there is no research examining recently diagnosed conditions. Our purpose was to evaluate this association in a large sample including the older population from Europe and Israel.

METHOD

Data from the Survey of Health, Ageing and Retirement in Europe COVID-19 Survey, a representative survey of individuals aged 50 or older residing in 27 European countries and Israel, were retrieved. Associations between recently diagnosed chronic conditions (ie, conditions detected over the last 3 years) (exposure) and hospitalization due to COVID-19 (outcome) were assessed using multivariable logistic regression.

RESULTS

A total of 51 514 participants on average 71.0 (SD = 9.2) years old were included. Participants with multimorbidity (ie, 2 or more recently diagnosed conditions) had significantly higher odds for COVID-19 hospitalization (adjusted odds ratio [AOR] = 3.91 [95% CI = 2.14-7.12]). Independent conditions such as lung disease (AOR = 16.94 [95% CI = 9.27-30.95]), heart disease (AOR = 3.29 [95% CI = 1.50-7.21]), or cancer (AOR = 3.45 [95% CI = 1.26-9.48]) showed particularly high odds for hospitalization due to COVID-19.

CONCLUSIONS

People with recently diagnosed diseases, and in particular those having lung disease, heart disease, or cancer, were significantly more likely to be hospitalized for COVID-19.

摘要

背景

仅有少数几项大样本量的研究探讨了慢性疾病与 2019 年冠状病毒病(COVID-19)住院之间的关系,且没有研究调查最近诊断出的疾病。我们的目的是在包括欧洲和以色列老年人在内的大样本中评估这种关联。

方法

检索了欧洲调查健康、衰老和退休研究 COVID-19 调查的数据,这是一项针对 27 个欧洲国家和以色列 50 岁或以上人群的代表性调查。使用多变量逻辑回归评估最近诊断的慢性疾病(即在过去 3 年内发现的疾病)(暴露)与因 COVID-19 住院(结局)之间的关联。

结果

共纳入 51514 名平均年龄为 71.0(SD=9.2)岁的参与者。患有多种合并症(即 2 种或多种最近诊断的疾病)的患者因 COVID-19 住院的可能性显著更高(调整后的优势比 [AOR] = 3.91 [95%CI=2.14-7.12])。独立疾病如肺病(AOR=16.94 [95%CI=9.27-30.95])、心脏病(AOR=3.29 [95%CI=1.50-7.21])或癌症(AOR=3.45 [95%CI=1.26-9.48])因 COVID-19 住院的可能性尤其高。

结论

患有最近诊断出的疾病的人,尤其是患有肺病、心脏病或癌症的人,因 COVID-19 住院的可能性显著更高。

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