Zhao Ning-Dong, Li Yu-Lin, Song Yu, Yang Bao-Jia, Ding Xiao, Gao Fang, Ye Jian, Hao Xiao-Jiang, Zhang Yu, Li Shun-Lin
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China; College of Chemistry and Engineering, Wenshan University, Wenshan 663000, PR China; College of Chemistry and Chemical Engineering, Chongqing University, Chongqing, 400044, PR China.
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China.
Fitoterapia. 2021 Sep;153:104989. doi: 10.1016/j.fitote.2021.104989. Epub 2021 Jul 9.
Ten new nortriterpenes, euphorbiumrins A-J (1-10), together with three known analogues (11-13) were isolated from the latex of Euphorbia resinifera. Their structures were established on the basis of extensive spectroscopic analyses (IR, UV, HRESIMS, 1D and 2D NMR). Their inhibitions on tomato yellow leaf curl virus (TYLCV) were evaluated and compound 5 exhibited significant anti-TYLCV activity with an inhibition rate of 71.7% at concentration of 40 μg/mL.
从树脂大戟的乳胶中分离出10种新的三萜类化合物，大戟素A-J（1-10），以及3种已知类似物（11-13）。通过广泛的光谱分析（红外、紫外、高分辨电喷雾电离质谱、一维和二维核磁共振）确定了它们的结构。评估了它们对番茄黄化曲叶病毒（TYLCV）的抑制作用，化合物5表现出显著的抗TYLCV活性，在浓度为40μg/mL时抑制率为71.7%。
