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结节病与结肠癌转移:诊断困境及PET扫描在监测疾病活动中的作用

Sarcoidosis vs. Colon Cancer Metastasis: Diagnostic Dilemma and the Role of PET Scan in Monitoring Disease Activity.

作者信息

Mahmood Raai, Al Banaa Kadhim, Ibrahim Israa, Hashim Ahmed, Torregrosa Luis

机构信息

Graduate Program, Ohio State University, Columbus, OH, USA.

Hemostasis and Thrombosis Department, University of California, San Diego, CA, USA.

出版信息

Case Rep Rheumatol. 2021 Apr 20;2021:5529523. doi: 10.1155/2021/5529523. eCollection 2021.

DOI:10.1155/2021/5529523
PMID:34258100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8244180/
Abstract

Sarcoidosis is a systemic inflammatory disorder characterized by "noncaseating granulomas." It primarily affects the lungs, but multiple other organs can be involved. Sarcoidosis has been increasingly reported in association with cancer. It can precede, follow or occur at the same time as the diagnosis of cancer. We report a case of sarcoidosis that was diagnosed concomitantly with colon cancer, highlighting the diagnostic dilemma of sarcoidosis vs. cancer metastasis, the relationship between the two, and the value of PET scan in follow-up and monitoring of disease activity.

摘要

结节病是一种以“非干酪样肉芽肿”为特征的全身性炎症性疾病。它主要影响肺部,但也可累及多个其他器官。结节病与癌症相关的报道越来越多。它可在癌症诊断之前、之后或同时出现。我们报告一例结节病与结肠癌同时诊断的病例,突出了结节病与癌症转移的诊断困境、两者之间的关系以及PET扫描在疾病活动随访和监测中的价值。

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Sarcoidosis vs. Colon Cancer Metastasis: Diagnostic Dilemma and the Role of PET Scan in Monitoring Disease Activity.结节病与结肠癌转移:诊断困境及PET扫描在监测疾病活动中的作用
Case Rep Rheumatol. 2021 Apr 20;2021:5529523. doi: 10.1155/2021/5529523. eCollection 2021.
2
Coexistence of sarcoidosis and metastatic lesions: A diagnostic and therapeutic dilemma.结节病与转移性病变并存:诊断与治疗的困境
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Gastrointestinal Manifestations of Sarcoidosis: A State-of-the-Art, Comprehensive Review of the Literature-Practical Clinical Insights and Many Unmet Needs on Diagnosis and Treatment.结节病的胃肠道表现:文献综述、实用临床见解及诊断与治疗中诸多未满足的需求
Pharmaceuticals (Basel). 2024 Aug 23;17(9):1106. doi: 10.3390/ph17091106.
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Multisystemic Sarcoidosis Presenting with Widespread Vertebral Osseous and Visceral Lesions Masquerading as Metastatic Disease: A Case Report and Literature Review.多系统肉样瘤病表现为广泛的脊柱骨和内脏病变,误诊为转移性疾病:病例报告及文献复习。
Am J Case Rep. 2022 Feb 7;23:e935158. doi: 10.12659/AJCR.935158.

本文引用的文献

1
PET/CT in the Diagnosis and Workup of Sarcoidosis: Focus on Atypical Manifestations.PET/CT 在结节病的诊断和研究中的应用:关注不典型表现。
Radiographics. 2018 Sep-Oct;38(5):1536-1549. doi: 10.1148/rg.2018180053. Epub 2018 Aug 17.
2
Coexistence of sarcoidosis and metastatic lesions: A diagnostic and therapeutic dilemma.结节病与转移性病变并存:诊断与治疗的困境
Oncol Lett. 2017 Dec;14(6):7643-7652. doi: 10.3892/ol.2017.7247. Epub 2017 Oct 20.
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Verifying Sarcoidosis Activity: Chitotriosidase versus ACE in Sarcoidosis - a Case-control Study.
验证结节病活动度:结节病中几丁质酶与血管紧张素转换酶的比较——一项病例对照研究
J Med Biochem. 2016 Nov 2;35(4):390-400. doi: 10.1515/jomb-2016-0017. eCollection 2016 Oct.
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Sarcoidosis and cancer risk: systematic review and meta-analysis of observational studies.结节病与癌症风险:观察性研究的系统评价和荟萃分析
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Immunopathogenesis of sarcoidosis and risk of malignancy: a lost truth?结节病的免疫发病机制和恶性肿瘤风险:被遗忘的真相?
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Intra-abdominal complications of sarcoidosis.结节病的腹腔内并发症。
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Elevated carcinoembryonic antigen and sarcoidosis masquerading as metastatic colon cancer.癌胚抗原升高和结节病伪装为转移性结肠癌。
Clin Colorectal Cancer. 2009 Jul;8(3):172-4. doi: 10.3816/CCC.2009.n.029.
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The anergic state in sarcoidosis is associated with diminished dendritic cell function.结节病中的无反应状态与树突状细胞功能减弱有关。
J Immunol. 2008 Jul 1;181(1):746-55. doi: 10.4049/jimmunol.181.1.746.
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Sarcoidosis and malignancy.结节病与恶性肿瘤。
Clin Dermatol. 2007 May-Jun;25(3):326-33. doi: 10.1016/j.clindermatol.2007.03.010.