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挪威普通实践中治疗抑郁症患者的趋势,2009-2015 年:基于全国登记的队列研究(挪威 GP-DEP 研究)。

Trends in treatment for patients with depression in general practice in Norway, 2009-2015: nationwide registry-based cohort study (The Norwegian GP-DEP Study).

机构信息

Research Unit for General Practice, NORCE Norwegian Research Centre, Årstadveien 17, N-5009, Bergen, Norway.

Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.

出版信息

BMC Health Serv Res. 2021 Jul 15;21(1):697. doi: 10.1186/s12913-021-06712-w.

Abstract

BACKGROUND

Depression is highly prevalent, but knowledge is scarce as to whether increased public awareness and strengthened government focus on mental health have changed how general practitioners (GPs) help their depressed patients. This study aimed to examine national time trends in GP depression care and whether trends varied regarding patient gender, age, and comorbidity.

METHODS

Nationwide registry-based cohort study, Norway. The study population comprised all residents aged 20 years or older with new depression diagnoses recorded in general practice, 2009-2015. We linked reimbursement claims data from all consultations in general practice for depression with information on demographics and antidepressant medication. The outcome was type(s) of GP depression care during 12 months from the date of diagnosis: (long) consultation, talking therapy, antidepressant drug treatment, sickness absence certification, and referral to secondary mental health care. Covariates were patient gender, age, and comorbidity. The data are presented as frequencies and tested with generalized linear models.

RESULTS

We included 365,947 new depression diagnoses. Mean patient age was 44 years (SD = 16), 61.9 % were women, 41.2 % had comorbidity. From 2009 to 2015, proportions of patients receiving talking therapy (42.3-63.4 %), long consultations (56.4-71.8 %), and referral to secondary care (16.6-21.6 %) increased, while those receiving drug treatment (31.3-25.9 %) and sick-listing (58.1-50 %) decreased. The trends were different for gender (women had a greater increase in talking therapy and a smaller decrease in sick-listing, compared to men), age (working-aged patients had a smaller increase in talking therapy, a greater increase in long consultations, and a smaller decrease in antidepressant drug use, compared to older patients) and comorbidity (patients with mental comorbidity had a smaller increase in talking therapy and a greater increase in long consultations, compared to those with no comorbidity and somatic comorbidity).

CONCLUSIONS

The observed time trends in GP depression care towards increased provision of psychological treatment and less drug treatment and sick-listing were in the desired direction according to Norwegian health care policy. However, the large and persistent differences in treatment rates between working-aged and older patients needs further investigation.

摘要

背景

抑郁症的发病率很高,但对于公众意识的提高和政府对心理健康的重视是否改变了全科医生(GP)帮助抑郁患者的方式,人们知之甚少。本研究旨在考察 GP 治疗抑郁症的全国时间趋势,以及这些趋势是否因患者性别、年龄和合并症的不同而有所不同。

方法

这是一项基于全国登记的队列研究,在挪威进行。研究人群包括所有 20 岁及以上在全科医疗中确诊新患抑郁症的居民,研究时间为 2009 年至 2015 年。我们将全科医疗中与抑郁症相关的所有咨询的报销索赔数据与人口统计学和抗抑郁药物信息相关联。结果是从诊断日期起 12 个月内 GP 治疗抑郁症的类型(长程咨询、谈话疗法、抗抑郁药物治疗、病假证明和转介到二级精神卫生保健)。协变量为患者性别、年龄和合并症。数据以频率表示,并使用广义线性模型进行检验。

结果

我们纳入了 365947 例新诊断的抑郁症。患者平均年龄为 44 岁(标准差=16),61.9%为女性,41.2%有合并症。2009 年至 2015 年,接受谈话疗法(42.3%-63.4%)、长程咨询(56.4%-71.8%)和转介到二级保健(16.6%-21.6%)的患者比例增加,而接受药物治疗(31.3%-25.9%)和病假(58.1%-50%)的患者比例下降。这些趋势在性别(与男性相比,女性接受谈话疗法的比例增加更多,病假的比例减少更少)、年龄(与老年患者相比,工作年龄段的患者接受谈话疗法的比例增加更少,长程咨询的比例增加更多,药物治疗的比例减少更少)和合并症(与无合并症和躯体合并症的患者相比,有精神合并症的患者接受谈话疗法的比例增加更少,长程咨询的比例增加更多)方面存在差异。

结论

根据挪威的医疗保健政策,观察到全科医生治疗抑郁症的时间趋势朝着增加心理治疗和减少药物治疗和病假的方向发展,这是令人满意的。然而,工作年龄段和老年患者之间治疗率的巨大且持续的差异需要进一步调查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0aef/8283991/28d6c989d6d5/12913_2021_6712_Fig1_HTML.jpg

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