Leonard B J, McNaughton B L, Barnes C A
Department of Psychology, University of Colorado, Boulder 80309.
Brain Res. 1987 Nov 3;425(1):174-7. doi: 10.1016/0006-8993(87)90496-3.
The influence of behavioral state on the induction of long-term enhancement (LTE) of hippocampal synapses was studied in chronically prepared animals. Perforant path evoked field potentials and EEG were recorded from fascia dentata during slow-wave sleep (SWS) and waking. LTE was strongly suppressed during SWS, suggesting that hippocampal information storage may be inactivated at certain phases of the sleep cycle. Normal LTE was observed in the same animals while awake.
在长期制备的动物中研究了行为状态对海马突触长期增强（LTE）诱导的影响。在慢波睡眠（SWS）和清醒期间，记录了齿状回的穿通通路诱发场电位和脑电图。在SWS期间，LTE受到强烈抑制，这表明海马信息存储可能在睡眠周期的某些阶段失活。在相同动物清醒时观察到正常的LTE。
